• Publications
  • Influence
Loss of endothelium-dependent relaxant activity in the pulmonary circulation of rats exposed to chronic hypoxia.
TLDR
It is demonstrated that hypoxia-induced pulmonary hypertension is associated with a loss of EDRF activity in pulmonary vessels, with a rapid recovery on return to a normoxic environment.
Ischemia and reperfusion-induced histologic changes in the rat retina. Demonstration of a free radical-mediated mechanism.
TLDR
The SOD and EGB 761 significantly reduced the development of reperfusion-induced retinal edema and significantly prevented the neutrophil leukocyte infiltration and had a protective effect against reperfusions-induced injury when these agents were administered just before reperfuse ("late" administration).
Ligation of CD23 triggers cAMP generation and release of inflammatory mediators in human monocytes.
TLDR
Results indicate that ligation of CD23 induces cAMP generation in CD23+ human monocytes and that CD23 may regulate the IgE-dependent functions in normal human monocyte.
BN 52021 and related compounds: A new series of highly specific PAF-acether receptor antagonists isolated from Ginkgo biloba L.
TLDR
PAF-acether is one of the most powerful platelet activators known inducing platelet shape change, aggregation and secretion and reduces coronary blood flow and contractile force of isolated guineapig hearth, leading to cardiac anaphylaxis.
...
...