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damnacanthal

An alkaloid phytochemical found in the Morinda Citrifolia (Noni) that inhibits the growth of RAS cancer cells. The exact mechanism is unknown but may… 
National Institutes of Health

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Broader (1)

Anthraquinones
Receptor Tyrosine Kinase Inhibition

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Src‐type tyrosine kinase p56lck is critical for thymic stromal lymphopoietin‐induced allergic rhinitis
Thymic stromal lymphopoietin (TSLP) is a regulator of mast cell‐mediated allergic inflammatory reactions, but the manner in which… 
2016
2016
Quassinoids: Viral protein R inhibitors from Picrasma javanica bark collected in Myanmar for HIV infection.
2015
2015
Cytotoxicity of anthraquinones from the roots of Pentas schimperi towards multi-factorial drug-resistant cancer cells
SummaryIntroduction Multidrug resistance in cancer represents a major problem in chemotherapy. The present study was designed to… 
Review
2014
Review
2014
Damnacanthal: a promising compound as a medicinal anthraquinone.
The Noni fruit, or scientifically known as Morinda citrifolia can be found in various parts of the world, especially in the… 
2012
2012
Damnacanthal from the Congolese Medicinal Plant Garcinia huillensis has a Potent Preferential Cytotoxicity against Human Pancreatic Cancer PANC‐1 Cells
Screening of eight Congolese medicinal plants showed that the CHCl3 and MeOH extracts of Aframomum melegueta (PC50 = 47.8 µg/mL… 
2011
2011
Damnacanthal-induced anti-inflammation is associated with inhibition of NF-κB activity.
Morinda citrifolia L. (Rubiaceae), commonly called noni, is a traditional folk medicinal plant with a long history of use for… 
2008
2008
Molecular pharmacology of adipocyte-secreted autotaxin.
2003
2003
Pharmacological and toxicological activity of Heterophyllaea pustulata anthraquinone extracts.
Benzenic extracts from both stems and leaves of Heterophyllaea pustulata showed the most significant activity in vivo in the… 
2003
2003
Cytotoxic Properties of Anthraquinones (Nordamnacanthal and Damnacanthal) from Roots of Morinda Elliptica
The study on the cytotoxic properties of nordamnacanthal and damnacanthal, the anthraquinones isolated from the roots of Morinda… 
Highly Cited
1995
Highly Cited
1995
Damnacanthal is a highly potent, selective inhibitor of p56lck tyrosine kinase activity.
Damnacanthal, an anthraquinone isolated from a plant extract, was found to be a potent, selective inhibitor of p56lck tyrosine… 
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