contortrostatin
National Institutes of Health
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Contortrostatin (CN) (Mr 13,500 Da) is a novel homodimeric disintegrin isolated from the venom of Agkistrodon contortrix…
Irttegrins play a major role in the regulation of cell motility. They physically link the extracellular environment to the…
BACKGROUND
The snake venom disintegrin contortrostatin has been shown to bind to integrins alpha IIb beta 3, alpha v beta 3…
Contortrostatin is a homodimeric disintegrin from snake venom. We have shown that contortrostatin binds to integrins…
Contortrostatin is a homodimeric disintegrin that inhibits platelet aggregation and cell adhesion to extracellular matrix…
We report that cells adhering to contortrostatin show transient increases in activation of Extracellular signal Regulated Kinase…
Disintegrins are small disulfide‐rich proteins containing an Arg‐Gly‐Asp (RGD) sequence near their carboxyl terminus. These…
Tyrosine phosphorylation of multiple platelet proteins is regulated by the integrin alpha IIb beta 3. In order to further examine…