constitutive secretory pathway

Known as: constitutive exocytosis 
A process of exocytosis found in all eukaryotic cells, in which transport vesicles destined for the plasma membrane leave the trans-Golgi network in… (More)
National Institutes of Health

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negative regulation of constitutive secretory pathway

Papers overview

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2006
2006
Lumenal protein sorting to the constitutive secretory pathway of a regulated secretory cell.
Newly synthesized secretory granule content proteins are delivered via the Golgi complex for storage within mature granules… (More)
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Review
2002
Review
2002
Neuroendocrine secretory protein 55: a novel marker for the constitutive secretory pathway.
The chromogranins constitute a class of acidic proteins comprising the structurally related chromogranins A and B and… (More)
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Highly Cited
2000
Highly Cited
2000
Imaging Constitutive Exocytosis with Total Internal Reflection Fluorescence Microscopy
Total internal reflection fluorescence microscopy has been applied to image the final stage of constitutive exocytosis, which is… (More)
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Highly Cited
2000
Highly Cited
2000
Neurotrophin-3 sorts to the constitutive secretory pathway of hippocampal neurons and is diverted to the regulated secretory pathway by coexpression with brain-derived neurotrophic factor.
Hippocampal neurons release nerve growth factor (NGF) through the constitutive secretory pathway, thus allowing the protein to be… (More)
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Review
1998
Review
1998
Subtilisin-related serine proteases in the mammalian constitutive secretory pathway.
Proteolytic cleavage is a key step in the activation of many secreted proteins. Since the identification of the prototype yeast… (More)
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Review
1998
Review
1998
The proprotein convertases.
The major endoproteolytic processing enzymes of the secretory pathway are the subtilisin-like proprotein convertases (SPCs… (More)
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1997
1997
Alpha1-antitrypsin Portland inhibits processing of precursors mediated by proprotein convertases primarily within the constitutive secretory pathway.
We studied the extent of cellular inhibitory activity of alpha1-antitrypsin Portland (alpha1-PDX), a potent inhibitor of… (More)
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Review
1994
Review
1994
Proinsulin processing in the regulated and the constitutive secretory pathway
Proinsulin is converted to insulin in betacell granules. Conversion involves endoproteolytic cleavage at the two pairs of basic… (More)
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1993
1993
Positional and additive effects of basic amino acids on processing of precursor proteins within the constitutive secretory pathway.
We have recently shown that the Arg/Lys-X-Lys/Arg-Arg or Arg/Lys-X-X-X-Lys/Arg-Arg sequence serves as a signal for cleavage of… (More)
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1992
1992
Sequence requirements for precursor cleavage within the constitutive secretory pathway.
We have recently demonstrated that the Arg-X-Lys/Arg-Arg sequence is a signal for precursor cleavage catalyzed by furin, a… (More)
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