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Insulin signalling and the regulation of glucose and lipid metabolism
- A. Saltiel, C. Kahn
- Medicine, BiologyNature
- 13 December 2001
The epidemic of type 2 diabetes and impaired glucose tolerance is one of the main causes of morbidity and mortality worldwide. In both disorders, tissues such as muscle, fat and liver become less…
Critical nodes in signalling pathways: insights into insulin action
- C. Taniguchi, B. Emanuelli, C. Kahn
- Computer ScienceNature Reviews Molecular Cell Biology
- 1 February 2006
TLDR
Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1
- J. C. Yoon, P. Puigserver, B. Spiegelman
- BiologyNature
- 13 September 2001
TLDR
Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1
- M. Patti, A. Butte, L. Mandarino
- Biology, MedicineProceedings of the National Academy of Sciences…
- 27 June 2003
TLDR
Suppression of Aging in Mice by the Hormone Klotho
- H. Kurosu, Masaya Yamamoto, M. Kuro-o
- BiologyScience
- 16 September 2005
TLDR
Type 2 diabetes mellitus
- R. DeFronzo, E. Ferrannini, R. Weiss
- Medicine, BiologyNature Reviews Disease Primers
- 23 July 2015
TLDR
SIRT 3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation
- M. Hirschey, T. Shimazu, E. Verdin
- Biology
- 2010
TLDR
Antioxidants prevent health-promoting effects of physical exercise in humans
- M. Ristow, K. Zarse, M. Blüher
- Medicine, BiologyProceedings of the National Academy of Sciences
- 26 May 2009
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