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concanamycin A

Known as: folimycin 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (3)

Antiviral AgentsEnzyme InhibitorsMacrolides

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Frequency-Dependent Modes of Synaptic Vesicle Endocytosis and Exocytosis at Adult Mouse Neuromuscular Junctions
During locomotion, adult rodent lumbar motoneurons fire in high-frequency (80–100 Hz) 1–2 s bursts every several seconds… 
Highly Cited
2010
Highly Cited
2010
Vesicular ATPase Inserted into the Plasma Membrane of Motor Terminals by Exocytosis Alkalinizes Cytosolic pH and Facilitates Endocytosis
Highly Cited
2004
Highly Cited
2004
Uptake of botulinum neurotoxin into cultured neurons.
Botulinum neurotoxins (BoNTs) act within the synaptic terminal to block neurotransmitter release. The toxin enters the neuron by… 
Highly Cited
2001
Highly Cited
2001
Three-color flow cytometric assay for the study of the mechanisms of cell-mediated cytotoxicity.
Highly Cited
1997
Highly Cited
1997
Degradation of  T Cell Receptor (TCR)–CD3-ζ Complexes after Antigenic Stimulation
T cell activation by specific antigen results in a rapid and long-lasting downregulation of triggered T cell receptors (TCRs). In… 
1997
1997
Characterization of a series of vacuolar type H(+)-ATPase inhibitors on CTL-mediated cytotoxicity.
Highly Cited
1996
Highly Cited
1996
Proton gradient formation in early endosomes from proximal tubules.
Highly Cited
1994
Highly Cited
1994
Destruxin B, a specific and readily reversible inhibitor of vacuolar-type H(+)-translocating ATPase.
Destruxin B, a peptide antibiotic, inhibits vacuolar-type ATPase (V-ATPase) specifically and dose-dependently among ATPases… 
Highly Cited
1994
Highly Cited
1994
Acidification is essential for maintaining the structure and function of lytic granules of CTL. Effect of concanamycin A, an inhibitor of vacuolar type H(+)-ATPase, on CTL-mediated cytotoxicity.
An inhibitor of vacuolar type H(+)-ATPase, concanamycin A (CMA), inhibited the specific cytolytic activity of a CD8+ CTL clone… 
Highly Cited
1984
Highly Cited
1984
Isolation and characterization of concanamycins A, B and C.
Concanamycins A, B and C were isolated from the mycelium of Streptomyces diastatochromogenes S-45 as effective inhibitors of the… 
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