V. Marshansky

Publications65
h-index30
Citations3,519
Highly Influential Citations152
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Renal vacuolar H+-ATPase.
TLDR
The importance in final urinary acidification along the collecting system is highlighted by monogenic defects in two subunits (ATP6V0A4, ATP6V1B1) of the vacuolar H(+)-ATPase in patients with distal renal tubular acidosis.
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The V-type H+-ATPase in vesicular trafficking: targeting, regulation and function
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V-ATPase interacts with ARNO and Arf6 in early endosomes and regulates the protein degradative pathway
TLDR
Data demonstrate the crucial role of early endosomal acidification and V-ATPase/ARNO/Arf6 interactions in the regulation of the endocytic degradative pathway and indicate that V-atPase could modulate membrane trafficking by recruiting and interacting with ARNO and Arf6; characteristics that are consistent with the role of V- ATPase as an essential component of theendosomal pH-sensing machinery.
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Eukaryotic V-ATPase: novel structural findings and functional insights.
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Remodeling the cellular profile of collecting ducts by chronic carbonic anhydrase inhibition.
TLDR
The cellular profile of the collecting ducts of adult rats can be remodeled by inhibiting CA activity in rats by using osmotic pumps containing acetazolamide, suggesting that CA activity plays an important role in determining the differentiated phenotype of medullary collecting duct epithelial cells.
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Distinct Expression Patterns of Different Subunit Isoforms of the V-ATPase in the Rat Epididymis1
TLDR
More than one isoform of subunit isoforms of the V-ATPase are present in the epididymal and vas deferens epithelium, confirming that narrow and clear cells are well fit for active proton secretion.
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The B1 Subunit of the H+ATPase Is a PDZ Domain-binding Protein
TLDR
The colocalization of NHE-RF and H+ATPase in B- but not A-intercalated cells suggests a role in generating, maintaining, or modulating the variable H+ ATPase polarity that characterizes the B-cell phenotype.
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Mapping the H+ (V)-ATPase interactome: identification of proteins involved in trafficking, folding, assembly and phosphorylation
V-ATPases (H+ ATPases) are multisubunit, ATP-dependent proton pumps that regulate pH homeostasis in virtually all eukaryotes. They are involved in key cell biological processes including vesicle…
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Postnatal Establishment of Allelic Gαs Silencing as a Plausible Explanation for Delayed Onset of Parathyroid Hormone Resistance Owing to Heterozygous Gαs Disruption
TLDR
It is determined that the manifestation of PTH resistance caused by the maternal loss of Gαs, ie, hypocalcemia and elevated serum PTH, occurs after early postnatal life, and this finding correlates well with the latency of P TH resistance in patients with PHP‐Ia.
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Proteasomes Modulate Balance Among Proapoptotic and Antiapoptotic Bcl-2 Family Members and Compromise Functioning of the Electron Transport Chain in Leukemic Cells1
TLDR
Results show that proteasomes can modulate apoptosis of lymphocytes by affecting the half-life of Bcl-2 family members, Bik being one of them.
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