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complement C4d

Known as: complement 4d, C4d, complement component 4d fragment 
C4d (380 aa, ~41 kDa) is a fragment of complement component-4. This protein plays a role in the regulation of the classical and lectin complement… 
National Institutes of Health

Related topics

Related topics

13 relations
C4d Ag:PrThr:Pt:Tiss:Ord:Immune stainComplement ActivationComplement C4d measurementComplement C4d:EntNum:Pt:RBC:Qn

Broader (3)

Complement C4bComplement component C4Peptide Fragments

Papers overview

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Review
2013
Review
2013
Antibody-mediated vascular rejection of kidney allografts: a population-based study
Highly Cited
2010
Highly Cited
2010
Evidence for Antibody-Mediated Injury as a Major Determinant of Late Kidney Allograft Failure
Background. Late graft failure (LGF) is believed to be the consequence of immunologic and nonimmunologic insults leading to… 
Highly Cited
2002
Highly Cited
2002
Acute humoral rejection in kidney transplantation: II. Morphology, immunopathology, and pathologic classification.
The incidence of acute humoral rejection (AHR) in renal allograft biopsies has been difficult to determine because widely… 
Highly Cited
2002
Highly Cited
2002
Capillary deposition of complement split product C4d in renal allografts is associated with basement membrane injury in peritubular and glomerular capillaries: a contribution of humoral immunity to…
Endothelial deposition of the complement split product C4d is an established marker of antibody-mediated acute renal allograft… 
Highly Cited
2002
Highly Cited
2002
Detection of the complement degradation product C4d in renal allografts: diagnostic and therapeutic implications.
The immunohistochemical detection of the complement degradation product C4d, a component of the classical complement pathway… 
Highly Cited
2002
Highly Cited
2002
Capillary C4d deposition in kidney allografts: a specific marker of alloantibody-dependent graft injury.
Capillary deposition of the complement split product C4d has been discussed as a marker for antibody-mediated kidney allograft… 
Highly Cited
2002
Highly Cited
2002
C4d deposition in acute rejection: an independent long-term prognostic factor.
Peritubular capillary deposition of C4d has been demonstrated to be associated with both acute humoral and vascular rejection and… 
Highly Cited
2001
Highly Cited
2001
Chronic humoral rejection: identification of antibody-mediated chronic renal allograft rejection by C4d deposits in peritubular capillaries.
The pathogenesis of chronic renal allograft rejection (CR) remains obscure. The hypothesis that a subset of CR is mediated by… 
Highly Cited
2001
Highly Cited
2001
Endothelial C4d deposition is associated with inferior kidney allograft outcome independently of cellular rejection.
BACKGROUND Capillary deposition of complement split product C4d has been suggested to be a valuable marker for humoral rejection… 
Highly Cited
1999
Highly Cited
1999
Complement activation in acute humoral renal allograft rejection: diagnostic significance of C4d deposits in peritubular capillaries.
The distinction between acute humoral rejection (AHR) and acute cellular rejection (ACR) in renal allografts is therapeutically… 
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