Skip to search form
Skip to main content
Skip to account menu
Semantic Scholar
Semantic Scholar's Logo
Search 205,245,499 papers from all fields of science
Search
Sign In
Create Free Account
collagenase Clostridium histolyticum
Known as:
collagenase I
, Clostridium histolyticum Collagenase
, Collagenase, Microbial
Expand
A metalloproteinase which degrades helical regions of native collagen to small fragments. Preferred cleavage is -Gly in the sequence -Pro-Xaa-Gly-Pro…
Expand
National Institutes of Health
Create Alert
Alert
Related topics
Related topics
16 relations
Burn injury
COLLAGENASE
COLLAGENASE 0.25 UNT/MG Topical Ointment
Drug Allergy
Expand
Narrower (2)
Xiaflex
iruxol
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2015
Highly Cited
2015
Clinical safety and effectiveness of collagenase clostridium histolyticum injection in patients with Peyronie's disease: a phase 3 open-label study.
L. Levine
,
B. Cuzin
,
+6 authors
D. Ralph
The journal of sexual medicine
2015
Corpus ID: 25001181
INTRODUCTION Collagenase clostridium histolyticum (CCH; Xiaflex, Auxilium Pharmaceuticals, Inc., Chesterbrook, PA, USA) is a Food…
Expand
Review
2013
Review
2013
Clinical efficacy, safety and tolerability of collagenase clostridium histolyticum for the treatment of peyronie disease in 2 large double-blind, randomized, placebo controlled phase 3 studies.
M. Gelbard
,
I. Goldstein
,
+6 authors
C. Carson
The Journal of urology
2013
Corpus ID: 7387304
Highly Cited
2013
Highly Cited
2013
Dupuytren contracture recurrence following treatment with collagenase clostridium histolyticum (CORDLESS study): 3-year data.
C. Peimer
,
P. Blazar
,
+6 authors
T. Lindau
The Journal of hand surgery
2013
Corpus ID: 23639900
Highly Cited
2013
Highly Cited
2013
Efficacy and safety of collagenase clostridium histolyticum injection for Dupuytren contracture: short-term results from 2 open-label studies.
J. Witthaut
,
G. Jones
,
N. Skrepnik
,
H. Kushner
,
A. Houston
,
T. Lindau
The Journal of hand surgery
2013
Corpus ID: 8165541
Highly Cited
2010
Highly Cited
2010
Injectable collagenase Clostridium histolyticum: a new nonsurgical treatment for Dupuytren's disease.
D. Gilpin
,
S. Coleman
,
S. Hall
,
A. Houston
,
J. Karrasch
,
Nigel Jones
The Journal of hand surgery
2010
Corpus ID: 12110175
Highly Cited
2009
Highly Cited
2009
Injectable collagenase clostridium histolyticum for Dupuytren's contracture.
L. Hurst
,
M. Badalamente
,
+5 authors
J. Rodzvilla
The New England journal of medicine
2009
Corpus ID: 23771087
BACKGROUND Dupuytren's disease limits hand function, diminishes the quality of life, and may ultimately disable the hand. Surgery…
Expand
Highly Cited
1999
Highly Cited
1999
Gene Duplication and Multiplicity of Collagenases in Clostridium histolyticum
O. Matsushita
,
C. Jung
,
S. Katayama
,
J. Minami
,
Yukie Takahashi
,
A. Okabe
Journal of bacteriology
1999
Corpus ID: 36783950
ABSTRACT Clostridium histolyticum collagenase contains a number of different active components. Previously we have shown thatcolH…
Expand
Highly Cited
1992
Highly Cited
1992
Identification and functional characterization of a TIA-1-related nucleolysin.
A. Kawakami
,
Q. Tian
,
X. Duan
,
M. Streuli
,
S. Schlossman
,
P. Anderson
Proceedings of the National Academy of Sciences…
1992
Corpus ID: 22286325
We recently reported the molecular cloning of a cytotoxic granule-associated RNA-binding protein designated TIA-1. The ability of…
Expand
Highly Cited
1990
Highly Cited
1990
Human neutrophil collagenase. A distinct gene product with homology to other matrix metalloproteinases.
K. Hasty
,
T. Pourmotabbed
,
+4 authors
C. Mainardi
The Journal of biological chemistry
1990
Corpus ID: 36639400
Highly Cited
1968
Highly Cited
1968
Purification and properties of clostridiopeptidase B (Clostripain).
W. Mitchell
,
W. F. Harrington
The Journal of biological chemistry
1968
Corpus ID: 10902281
By clicking accept or continuing to use the site, you agree to the terms outlined in our
Privacy Policy
,
Terms of Service
, and
Dataset License
ACCEPT & CONTINUE