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collagenase Clostridium histolyticum

Known as: collagenase I, Clostridium histolyticum Collagenase, Collagenase, Microbial 
A metalloproteinase which degrades helical regions of native collagen to small fragments. Preferred cleavage is -Gly in the sequence -Pro-Xaa-Gly-Pro… 
National Institutes of Health

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Burn injuryCOLLAGENASECOLLAGENASE 0.25 UNT/MG Topical OintmentDrug Allergy

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Papers overview

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Highly Cited
2015
Highly Cited
2015
Clinical safety and effectiveness of collagenase clostridium histolyticum injection in patients with Peyronie's disease: a phase 3 open-label study.
INTRODUCTION Collagenase clostridium histolyticum (CCH; Xiaflex, Auxilium Pharmaceuticals, Inc., Chesterbrook, PA, USA) is a Food… 
Review
2013
Review
2013
Clinical efficacy, safety and tolerability of collagenase clostridium histolyticum for the treatment of peyronie disease in 2 large double-blind, randomized, placebo controlled phase 3 studies.
Highly Cited
2013
Highly Cited
2013
Dupuytren contracture recurrence following treatment with collagenase clostridium histolyticum (CORDLESS study): 3-year data.
Highly Cited
2013
Highly Cited
2013
Efficacy and safety of collagenase clostridium histolyticum injection for Dupuytren contracture: short-term results from 2 open-label studies.
Highly Cited
2010
Highly Cited
2010
Injectable collagenase Clostridium histolyticum: a new nonsurgical treatment for Dupuytren's disease.
Highly Cited
2009
Highly Cited
2009
Injectable collagenase clostridium histolyticum for Dupuytren's contracture.
BACKGROUND Dupuytren's disease limits hand function, diminishes the quality of life, and may ultimately disable the hand. Surgery… 
Highly Cited
1999
Highly Cited
1999
Gene Duplication and Multiplicity of Collagenases in Clostridium histolyticum
ABSTRACT Clostridium histolyticum collagenase contains a number of different active components. Previously we have shown thatcolH… 
Highly Cited
1992
Highly Cited
1992
Identification and functional characterization of a TIA-1-related nucleolysin.
We recently reported the molecular cloning of a cytotoxic granule-associated RNA-binding protein designated TIA-1. The ability of… 
Highly Cited
1990
Highly Cited
1990
Human neutrophil collagenase. A distinct gene product with homology to other matrix metalloproteinases.
Highly Cited
1968
Highly Cited
1968
Purification and properties of clostridiopeptidase B (Clostripain).
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