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chromosome loss

National Institutes of Health

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Chromosome Deletion

Papers overview

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Highly Cited
2008
Highly Cited
2008
Altered Dosage and Mislocalization of Histone H3 and Cse4p Lead to Chromosome Loss in Saccharomyces cerevisiae
Cse4p is an essential histone H3 variant in Saccharomyces cerevisiae that defines centromere identity and is required for proper… Expand
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Highly Cited
2007
Highly Cited
2007
X chromosome loss and ageing
The detection of a low level 45,X cell line during routine cytogenetic analysis in an adult female can be difficult to interpret… Expand
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Highly Cited
2007
Highly Cited
2007
Preferential X chromosome loss but random inactivation characterize primary biliary cirrhosis
Recent work has demonstrated enhanced X monosomy in women with primary biliary cirrhosis (PBC) as well as two other female… Expand
Review
2000
Review
2000
The in vitro micronucleus technique.
  • M. Fenech
  • Mutation research
  • 2000
    • Corpus ID: 24974343
The study of DNA damage at the chromosome level is an essential part of genetic toxicology because chromosomal mutation is an… Expand
Review
1997
Review
1997
The in vitro micronucleus test: a multi-endpoint assay to detect simultaneously mitotic delay, apoptosis, chromosome breakage, chromosome loss and non-disjunction.
Genotoxicity testing aims to detect a large range of genetic damage endpoints and evaluate such results in context of cell… Expand
Highly Cited
1996
Highly Cited
1996
The mismatch repair system reduces meiotic homeologous recombination and stimulates recombination-dependent chromosome loss
Efficient genetic recombination requires near-perfect homology between participating molecules. Sequence divergence reduces the… Expand
Highly Cited
1994
Highly Cited
1994
Basal cell carcinomas and squamous cell carcinomas of human skin show distinct patterns of chromosome loss.
Although basal cell carcinomas and squamous cell carcinomas are clinically and pathologically distinct, the molecular basis for… Expand
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Highly Cited
1993
Highly Cited
1993
Loss of a yeast telomere: Arrest, recovery, and chromosome loss
Yeast strains were constructed in which a single telomere could be eliminated from the end of a dispensable chromosome. In wild… Expand
Highly Cited
1989
Highly Cited
1989
A mutant with a defect in telomere elongation leads to senescence in yeast
We describe a general assay designed to detect mutants of yeast that are defective for any of several aspects of telomere… Expand
Highly Cited
1989
Highly Cited
1989
Kinetochore detection in micronuclei: an alternative method for measuring chromosome loss.
Whole chromosomes within micronuclei (MN) in cytokinesis-blocked human lymphocytes were detected by using anti-kinetochore… Expand
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