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chlorothricin

 
National Institutes of Health

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Aminoglycosides

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Highly Cited
2011
Highly Cited
2011
Abyssomicin Biosynthesis: Formation of an Unusual Polyketide, Antibiotic-Feeding Studies and Genetic Analysis
Abyssomicin C, produced by the marine actinomycete Verrucosispora maris AB-18-032, is active against Gram-positive bacteria… Expand
Highly Cited
2008
Highly Cited
2008
Cloning and characterization of the tetrocarcin A gene cluster from Micromonospora chalcea NRRL 11289 reveals a highly conserved strategy for tetronate biosynthesis in spirotetronate antibiotics.
Tetrocarcin A (TCA), produced by Micromonospora chalcea NRRL 11289, is a spirotetronate antibiotic with potent antitumor activity… Expand
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Highly Cited
2007
Highly Cited
2007
Elucidation of the kijanimicin gene cluster: insights into the biosynthesis of spirotetronate antibiotics and nitrosugars.
The antibiotic kijanimicin produced by the actinomycete Actinomadura kijaniata has a broad spectrum of bioactivities as well as a… Expand
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Highly Cited
2006
Highly Cited
2006
Genetic characterization of the chlorothricin gene cluster as a model for spirotetronate antibiotic biosynthesis.
The biosynthetic gene cluster for chlorothricin (CHL) was localized to a 122 kb contiguous DNA from Streptomyces antibioticus DSM… Expand
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1986
1986
Further studies on the biosynthesis of chlorothricin.
Feeding experiments with [U-13C3]- and (2R)-[1-2H2]glycerol showed that glycerol is incorporated intact into carbon atoms 22, 23… Expand
1981
1981
Biosynthesis of the macrolide antibiotic chlorothricin.
Feeding experiments with 13C-labeled precursors followed by 13C NMR analysis of the antibiotic and its aglycon have established a… Expand
1978
1978
Biosynthesis of the macrolide antibiotic chlorothricin: basic building blocks.
The biosynthesis of chlorothricin (I), a macrolide antibiotic isolated from Streptomyces antibioticus Tü 99, has been studied by… Expand
1975
1975
Chlorothricin, and inhibitor of porcine-heart malate dehydrogenases, discriminating between the mitochondrial and cytoplasmic isoenzyme.
  • P. Schindler
  • European journal of biochemistry
  • 1975
    • Corpus ID: 2948188
The macrolide-type antibiotic chlorothricin was found to inhibit both the mitochondrial and the cytoplasmic form of pig heart… Expand
1975
1975
Mode of action of the macrolide-type antibiotic, chlorothricin. Effect of the antibiotic on the catalytic activity and some structural parameters of pyruvate carboxylases purified from rat and…
The macrolide-type antibiotic chlorothricin inhibits pyruvate carboxylases purified from rat liver, chicken liver and Azotobacter… Expand
1972
1972
Interaction of antibiotics with membranes: chlorothricin.
Abstract The mode of interaction of the antibiotic chlorothricin with cell membranes has been studied using lecithin-water… Expand
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