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chlorothricin

National Institutes of Health

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Aminoglycosides

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2019
2019
Insights into the Functionalization of the Methylsalicyclic Moiety during the Biosynthesis of Chlorothricin by Comparative Kinetic Assays of the Activities of Two KAS III‐like Acyltransferases
Chlorothricin (CHL), an archetypal member of the family of spirotetronate antibiotics, possesses a tetronate-containing… 
2008
2008
[Isolation and study of antibiotic INA-1132 (chlorothricin), produced by actinomycete strain].
Taxonomic properties of strain INA-1132 producing antibiotic INA-1132 are described. The antibiotic showed activity against… 
1993
1993
Tetronothiodin, a novel cholecystokinin type-B receptor antagonist produced by Streptomyces sp. NR0489. III. Structural elucidation.
Tetronothiodin (1) is a potent and selective cholecystokinin type B (CCK-B) receptor antagonist produced by Streptomyces sp… 
1992
1992
New cholesterol biosynthesis inhibitors MC-031 (O-demethylchlorothricin), -032 (O-demethylhydroxychlorothricin), -033 and -034.
In the course of our screening for microbial compounds which possessed inhibitory activities against biosynthesis of cholesterol… 
1992
1992
Tetronothiodin, a novel cholecystokinin type-B receptor antagonist produced by Streptomyces sp.
Tetronothiodin (1) is a potent and selective cholecystokinin type B (CCK-B) receptor antagonist produced by Streptomyces sp… 
1986
1986
Further studies on the biosynthesis of chlorothricin.
Feeding experiments with [U-13C3]- and (2R)-[1-2H2]glycerol showed that glycerol is incorporated intact into carbon atoms 22, 23… 
1981
1981
Biosynthesis of the macrolide antibiotic chlorothricin.
Feeding experiments with 13C-labeled precursors followed by 13C NMR analysis of the antibiotic and its aglycon have established a… 
1978
1978
Biosynthesis of the macrolide antibiotic chlorothricin: basic building blocks.
The biosynthesis of chlorothricin (I), a macrolide antibiotic isolated from Streptomyces antibioticus Tü 99, has been studied by… 
1975
1975
Mode of action of the macrolide-type antibiotic, chlorothricin. Effect of the antibiotic on the catalytic activity and some structural parameters of pyruvate carboxylases purified from rat and…
The macrolide-type antibiotic chlorothricin inhibits pyruvate carboxylases purified from rat liver, chicken liver and Azotobacter… 
1972
1972
Interaction of antibiotics with membranes: chlorothricin.
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