chlorothricin

Tetronate antibiotics comprise an important and growing family of polyketide natural products possessing a characteristic… (More)

The enzymes 6-methylsalicylic acid (6-MSA) synthases (6-MSASs) are involved in the building of an aryl moiety in many bioactive… (More)

The biosynthetic pathway to the unusual tetronate ring of certain polyketide natural products, including the antibiotics… (More)

Taxonomic properties of strain INA-1132 producing antibiotic INA-1132 are described. The antibiotic showed activity against… (More)

The biosynthetic gene cluster for chlorothricin (CHL) was localized to a 122 kb contiguous DNA from Streptomyces antibioticus DSM… (More)

In the course of our screening for microbial compounds which possessed inhibitory activities against biosynthesis of cholesterol… (More)

Feeding experiments with [U-13C3]- and (2R)-[1-2H2]glycerol showed that glycerol is incorporated intact into carbon atoms 22, 23… (More)

Feeding experiments with 13C-labeled precursors followed by 13C NMR analysis of the antibiotic and its aglycon have established a… (More)

The biosynthesis of chlorothricin (I), a macrolide antibiotic isolated from Streptomyces antibioticus Tü 99, has been studied by… (More)

The macrolide-type antibiotic chlorothricin was found to inhibit both the mitochondrial and the cytoplasmic form of pig heart… (More)