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cetuximab

Known as: Cetuximab [Chemical/Ingredient], Anti-EGFR Monoclonal Antibody, Anti-Epidermal Growth Factor Receptor Monoclonal Antibody 
A recombinant, chimeric monoclonal antibody directed against the epidermal growth factor (EGFR) with antineoplastic activity. Cetuximab binds to the… Expand
National Institutes of Health

Papers overview

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Review
2019
Review
2019
Metastatic colorectal cancer (mCRC) remains incurable in most cases, but survival has improved with advances in cytotoxic… Expand
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Review
2017
Review
2017
Hypersensitivity reactions (HSRs) to monoclonal antibodies (mAbs) are increasingly frequent as this class of therapeutic agents… Expand
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Highly Cited
2009
Highly Cited
2009
BACKGROUND We investigated the efficacy of cetuximab plus irinotecan, fluorouracil, and leucovorin (FOLFIRI) as first-line… Expand
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Highly Cited
2009
Highly Cited
2009
BACKGROUND Fluoropyrimidine-based chemotherapy plus the anti-vascular endothelial growth factor (VEGF) antibody bevacizumab is… Expand
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Highly Cited
2008
Highly Cited
2008
BACKGROUND Cetuximab is effective in platinum-resistant recurrent or metastatic squamous-cell carcinoma of the head and neck. We… Expand
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Highly Cited
2008
Highly Cited
2008
BACKGROUND Treatment with cetuximab, a monoclonal antibody directed against the epidermal growth factor receptor, improves… Expand
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Highly Cited
2006
Highly Cited
2006
BACKGROUND We conducted a multinational, randomized study to compare radiotherapy alone with radiotherapy plus cetuximab, a… Expand
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Highly Cited
2006
Highly Cited
2006
The anti-epidermal growth factor receptor (anti-EGFR) cetuximab has been proven to be efficient in metastatic colorectal cancer… Expand
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Highly Cited
2004
Highly Cited
2004
BACKGROUND The epidermal growth factor receptor (EGFR), which participates in signaling pathways that are deregulated in cancer… Expand
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Highly Cited
2004
Highly Cited
2004
PURPOSE To evaluate the antitumor activity and toxicity of single-agent cetuximab in patients with chemotherapy-refractory… Expand
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