IMC C225

Known as: IMC-C225, C225 monoclonal antibody, monoclonal antibody C225 
 
National Institutes of Health

Papers overview

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Highly Cited
2002
Highly Cited
2002
Colon carcinomas frequently express the epidermal growth factor receptor (EGFR), and this expression correlates with more… (More)
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2002
2002
PURPOSE To investigate treatment of human pancreatic cancer cell lines and xenografts with combinations of Erbitux (IMC-C225… (More)
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Review
2001
Review
2001
Treatment of solid tumors despite improved techniques in detection, surgery, radiation therapy, and chemotherapy remains… (More)
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Review
2001
Review
2001
Squamous cell carcinoma (SCC) of the head and neck (H&N) remains a clinical challenge due to its high rate of locoregional… (More)
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Highly Cited
2000
Highly Cited
2000
PURPOSE The epidermal growth factor (EGF) receptor is frequently overexpressed in epithelial tumors. C225 is a human-to-murine… (More)
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Highly Cited
2000
Highly Cited
2000
Overexpression of epidermal growth factor receptor (EGFR) has been correlated with tumor resistance to cytotoxic agents… (More)
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Highly Cited
2000
Highly Cited
2000
Both epidermal growth factor receptor (EGF-R) signaling mechanisms and angiogenesis have been evaluated as independent targets… (More)
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2000
2000
BACKGROUND Pancreatic carcinoma is associated with a poor prognosis, and treatment options for patients with this disease are… (More)
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Highly Cited
1999
Highly Cited
1999
Epidermal growth factor (EGF)-related proteins such as transforming growth factor alpha (TGF-alpha) control cancer cell growth… (More)
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Highly Cited
1996
Highly Cited
1996
For prostate cancer, a correlation exists between overexpression of the epidermal growth factor receptor (EGFR) and poor clinical… (More)
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