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Bleomycin in the Treatment of Keloids and Hypertrophic Scars by Multiple Needle Punctures
BACKGROUND The treatment of keloids and hypertrophic scars has been difficult and a recent French study showed that bleomycin has been useful in the treatment of these lesions. OBJECTIVE To determineExpand
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An imbalance in Akt/mTOR is involved in the apoptotic and acantholytic processes in a mouse model of pemphigus vulgaris
Abstract:  Pemphigus vulgaris (PV) is an autoimmune blistering disease characterized by the presence of IgG autoantibodies against Dsg3. Our aim was to investigate the molecular events implicated inExpand
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In vivo blockade of pemphigus vulgaris acantholysis by inhibition of intracellular signal transduction cascades
Background  Pemphigus vulgaris (PV) is an autoimmune disease characterized by mucocutaneous intraepithelial blisters and pathogenic autoantibodies against desmoglein 3. The mechanism of blisterExpand
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Acneiform lesions secondary to ZD1839, an inhibitor of the epidermal growth factor receptor
Drugs that inhibit the epidermal growth factor receptor, such as ZD1839 or C225, are being used increasingly in the treatment of solid tumours. This has led to the appearance of new secondaryExpand
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Effects of low concentrations of cis‐ and trans‐urocanic acid on cytokine elaboration by keratinocytes
The urocanic acid cis isomer (cis‐UCA) is a possible cutaneous photoreceptor for the immunomodulatory phenomena that follow ultraviolet B irradiation. Several experiments in animals show anExpand
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Prospective study of percutaneous radiofrequency sympathicolysis in severe hyperhidrosis and facial blushing: efficacy and safety findings.
OBJECTIVE Hyperhidrosis (Hh) and facial blushing (Fb) are conditions caused by hyperactivity of the sympathetic system; they affect around 2% of the population. Severe cases have been typicallyExpand
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Skin cancer in heart transplant recipients.
BACKGROUND The frequency of skin cancer in organ transplant recipients is high, up to 15%. OBJECTIVE Our purpose was to determine the incidence of skin cancer in patients who underwentExpand
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The desmosome and hemidesmosome in cutaneous autoimmunity.
Epidermal blister formation is the hallmark of three cutaneous autoimmune diseases: pemphigus foliaceous (PF), pemphigus vulgaris (PV) and bullous pemphigoid (BP). In PF and PV, blistering is due toExpand
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