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ceftaroline fosamil

Known as: (6R,7R)-7-[(2Z)-2-ethoxyimino-2-[5-(phosphonoamino)-1,2,4-thiadiazol-3-yl]acetyl]amino]-3-[4-(1-methylpyridin-1-ium-4-yl)-1,3-thiazol-2-yl]sulfanyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate, Ceftarolinum fosamilum, (6R,7R)-7-(((2Z)-(Ethoxyimino)(5-(phosphonoamino)-1,2,4-thiadiazol-3-yl)acetyl)amino)-3-((4-(1-methylpyridinium-4-yl)thiazol-2-yl)sulfanyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-2-carboxylate Monoacetate Monohydrate 
An N-phosphono prodrug of the fifth-generation cephalosporin derivative ceftaroline with antibacterial activity. Ceftaroline fosamil is hydrolyzed to… 
National Institutes of Health

Related topics

Related topics

5 relations

Broader (1)

PPI-0903
TAK-599ceftaroline fosamil 400 MG Injection [Teflaro]ceftaroline fosamil acetate

Narrower (1)

Teflaro

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Macrolide therapy for community-acquired pneumonia due to atypical pathogens: outcome assessment at an early time point.
2016
2016
Outpatient use of ceftaroline fosamil versus vancomycin for osteoarticular infection: a matched cohort study.
OBJECTIVES There are few convenient intravenous options for long-term outpatient treatment of osteoarticular infection (OAI) and… 
2015
2015
Effect of age and sex on the pharmacokinetics and safety of avibactam in healthy volunteers.
2015
2015
Evaluation of the pharmacokinetics and safety of single and multiple ceftaroline fosamil infusions in healthy Chinese and Western subjects.
OBJECTIVES Two phase I studies in healthy Chinese (NCT01458743) and Western (NCT01612507) subjects evaluated the pharmacokinetics… 
2014
2014
Assessment of Time to Clinical Response, a Proxy for Discharge Readiness, among Hospitalized Patients with Community-Acquired Pneumonia Who Received either Ceftaroline Fosamil or Ceftriaxone in Two…
ABSTRACT The primary driver of health care costs for patients with community-acquired pneumonia (CAP) is the hospital length of… 
2014
2014
Comparison of In Vivo and In Vitro Pharmacodynamics of a Humanized Regimen of 600 Milligrams of Ceftaroline Fosamil Every 12 Hours against Staphylococcus aureus at Initial Inocula of 106 and 108 CFU…
ABSTRACT In light of the in vivo/in vitro discordance among beta-lactams against Gram-negative pathogens, we compared the in vivo… 
2013
2013
Spectrum and potency of ceftaroline tested against leading pathogens causing community-acquired respiratory tract infections in Europe (2010).
2013
2013
Interim susceptibility testing for ceftaroline, a new MRSA-active cephalosporin: selecting potent surrogate β-lactam markers to predict ceftaroline activity against clinically indicated species.
Review
2013
Review
2013
Current treatment of community-acquired pneumonia
Introduction: Community-acquired pneumonia (CAP) is a leading cause of morbidity and mortality worldwide. Management decisions… 
Review
2012
Review
2012
Ceftaroline applications for therapy in the United States.
The emergence of clinically important antimicrobial resistance continues to escalate, involving greater numbers of pathogens… 
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