cefpirome

Known as: 5H-1-Pyrindinium, 1-((7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-2-carboxy-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-3-yl)methyl)-5,6,7,8-tetrahydro-, hydroxide, inner salt, (6R-(6alpha,7beta(Z)))-, 3-((2,3-cyclopenteno-1-pyridinium)methyl)-7-(2-syn-methoximino-2-(2-aminothiazole-4-yl)acetamido)ceph-3-em-4-carboxylate, Cefpiroma 
A semisynthetic, broad-spectrum, fourth-generation cephalosporin with antibacterial activity. Cefpirome binds to and inactivates penicillin-binding… (More)
National Institutes of Health

Papers overview

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Highly Cited
2005
Highly Cited
2005
This study was conducted to evaluate the relationship between antimicrobial resistance and antimicrobial use in a university… (More)
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2004
2004
Enterobacter aerogenes develops increased multidrug resistance via a functional alteration of outer-membrane permeability… (More)
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Highly Cited
2002
Highly Cited
2002
Therapeutic options for infections caused by gram-negative organisms expressing plasmid-mediated AmpC beta-lactamases are limited… (More)
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2002
2002
OBJECTIVE Broad initial antibiotic treatment is crucial for patients experiencing septic shock or severe sepsis. Fourth… (More)
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2001
2001
Objectives: To measure plasma levels and pharmacokinetics of cefpirome in critically ill septic patients with normal renal… (More)
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Highly Cited
1999
Highly Cited
1999
While meropenem MICs were strongly influenced by the presence or absence of the MexAB-OprM efflux pump in both OprD-proficient… (More)
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Highly Cited
1999
Highly Cited
1999
Two clinical isolates of extended-spectrum beta-lactamase (ESBL)-producing Klebsiella pneumoniae were noted to be less… (More)
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1998
1998
The sporadic emergence of Klebsiella pneumoniae strains resistant to cefepime and cefpirome was observed in Greek hospitals… (More)
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Highly Cited
1995
Highly Cited
1995
Three types of multiple-drug-resistant mutants which were phenotypically similar to previously described nalB, nfxB, and nfxC… (More)
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Review
1993
Review
1993
Cefpirome is a new cephalosporin that exhibits similar in vitro potency to ceftazidime against Gram-negative organisms but has… (More)
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