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cefpirome

Known as: 5H-1-Pyrindinium, 1-((7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-2-carboxy-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-3-yl)methyl)-5,6,7,8-tetrahydro-, hydroxide, inner salt, (6R-(6alpha,7beta(Z)))-, 3-((2,3-cyclopenteno-1-pyridinium)methyl)-7-(2-syn-methoximino-2-(2-aminothiazole-4-yl)acetamido)ceph-3-em-4-carboxylate, Cefpiroma 
A semisynthetic, broad-spectrum, fourth-generation cephalosporin with antibacterial activity. Cefpirome binds to and inactivates penicillin-binding… 
National Institutes of Health

Related topics

Related topics

5 relations

Broader (2)

Anti-Bacterial AgentsCephalosporins
CEFPIROME SULFATECefpirome:Susceptibility:Point in time:Isolate:Quantitative:MINIMUM LETHAL CONCENTRATION

Narrower (1)

HR 810

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Antibiotic sensitivity pattern of bacterial pathogens in the intensive care unit of Fatmawati Hospital, Indonesia.
Highly Cited
2005
Highly Cited
2005
Relationships between antimicrobial use and antimicrobial resistance in Gram-negative bacteria causing nosocomial infections from 1991–2003 at a university hospital in Taiwan
Highly Cited
2001
Highly Cited
2001
Oxacillinase-Mediated Resistance to Cefepime and Susceptibility to Ceftazidime in Pseudomonas aeruginosa
ABSTRACT Pseudomonas aeruginosa clinical isolate SOF-1 was resistant to cefepime and susceptible to ceftazidime. This resistance… 
Highly Cited
2001
Highly Cited
2001
Extension of resistance to cefepime and cefpirome associated to a six amino acid deletion in the H-10 helix of the cephalosporinase of an Enterobacter cloacae clinical isolate.
Enterobacter cloacae CHE, a clinical strain with overproduced cephalosporinase was found to be highly resistant to the new… 
Highly Cited
1999
Highly Cited
1999
Carbapenem Activities against Pseudomonas aeruginosa: Respective Contributions of OprD and Efflux Systems
ABSTRACT While meropenem MICs were strongly influenced by the presence or absence of the MexAB-OprM efflux pump in both OprD… 
Review
1998
Review
1998
Important and emerging beta-lactamase-mediated resistances in hospital-based pathogens: the Amp C enzymes.
Highly Cited
1995
Highly Cited
1995
Outer membrane proteins responsible for multiple drug resistance in Pseudomonas aeruginosa
Three types of multiple-drug-resistant mutants which were phenotypically similar to previously described nalB, nfxB, and nfxC… 
Highly Cited
1994
Highly Cited
1994
Cefquinome (HR 111V). In vitro evaluation of a broad-spectrum cephalosporin indicated for infections in animals.
Highly Cited
1994
Highly Cited
1994
Conditions for the emergence of resistance to cefpirome and ceftazidime in experimental endocarditis due to Pseudomonas aeruginosa.
The conditions for the emergence of resistance to cefpirome and ceftazidime were studied in rabbits with experimental aortic… 
Highly Cited
1993
Highly Cited
1993
Evaluation of antimicrobial regimens for treatment of experimental penicillin- and cephalosporin-resistant pneumococcal meningitis
The most appropriate therapy for meningitis caused by Streptococcus pneumoniae strains resistant to the extended-spectrum… 
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