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casticin

Known as: 3',5-dihydroxy-3,4',6,7-tetramethoxyflavone, vitexicarpin 
National Institutes of Health

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Broader (1)

Flavonoids

Papers overview

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2019
2019
Casticin Induces DNA Damage and Impairs DNA Repair in Human Bladder Cancer TSGH-8301 Cells
Background/Aim: Casticin shows anti-cancer effects in many types of cancer. However, there is no information regarding its role… 
2016
2016
Casticin induces DNA damage and inhibits DNA repair-associated protein expression in B16F10 mouse melanoma cancer cells.
Casticin, a polymethoxyflavone, has been demonstrated to possess anticancer activities, yet no study has shown in detail that… 
2016
2016
Casticin Induced Apoptosis in A375.S2 Human Melanoma Cells through the Inhibition of NF-[Formula: see text]B and Mitochondria-Dependent Pathways In Vitro and Inhibited Human Melanoma Xenografts in a…
Casticin, a polymethoxyflavone occurring in natural plants, has been shown to have anticancer activities. In the present study… 
2015
2015
Synergistic Anti-tumoral Effect of Achillea millefolium Combined with Bleomycin on Prostate Cancer Cells
Background: The aim of this study was to investigate the effec t of methanolic extract of Achillea millefolium L. (MEA) on the… 
2014
2014
Activation of the apoptosis signal-regulating kinase 1/c-Jun N-terminal kinase pathway is involved in the casticin-induced apoptosis of colon cancer cells
Casticin is one of the main components of the fruits of Vitex rotundifolia L. Studies have shown that casticin inhibits the… 
2013
2013
Regiospecific Methylation of a Dietary Flavonoid Scaffold Selectively Enhances IL-1β Production following Toll-like Receptor 2 Stimulation in THP-1 Monocytes
Background: Plant natural products typically contain regiospecific modifications in their side chains that lead to different… 
2012
2012
Microarray-based mRNA expression profiling of leukemia cells treated with the flavonoid, casticin.
Natural polyphenols play an important role in tumor inhibition. We used a doxorubicin-sensitive acute T-lymphoblastic leukemia… 
2011
2011
Proliferation inhibition of human cervical cancer HeLa cells by Casticin in vitro
ObjectiveThe aim of the study was to investigate the effect of Casticin on proliferation inhibition of human cervical cancer HeLa… 
2010
2010
[Vitexicarpin affects proliferation and apoptosis in mutated p53 breast cancer cell].
OBJECTIVE To elucidate the effect of proliferation and apoptosis induced by vitexicarpin in mutated p53 Hs578T cell line and… 
2000
2000
New eudesmane sesquiterpenes from Plectranthus cylindraceus.
Three new eudesmane sesquiterpenes, plectranthone (1), desacetylplectranthone (2), isodeacetylplectranthone (3), and the three… 
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