caspase-7

Known as: MCH3, Protease Mch-3, Apoptotic, CMH-1 
A short pro-domain caspase that plays an effector role in APOPTOSIS. It is activated by INITIATOR CASPASES such as CASPASE 3 and CASPASE 10. Several… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1985-2017
05010019852017

Papers overview

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Highly Cited
2012
Highly Cited
2012
Apoptosis is a form of programmed cell death that is regulated by the Bcl-2 family and caspase family of proteins. The caspase… (More)
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Highly Cited
2008
Highly Cited
2008
Members of the caspase family of cysteine proteases play central roles in coordinating the stereotypical events that occur during… (More)
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Highly Cited
2008
Highly Cited
2008
The aspartate-specific cysteine protease caspase-1 is activated by the inflammasomes and is responsible for the proteolytic… (More)
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Highly Cited
2003
Highly Cited
2003
A large number of correlative studies have established that the activation of the unfolded protein response (UPR) alters the cell… (More)
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Highly Cited
2001
Highly Cited
2001
The inhibitor of apoptosis (IAP) proteins suppress cell death by inhibiting the catalytic activity of caspases. Here we present… (More)
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Highly Cited
2001
Highly Cited
2001
The inhibitor of apoptosis proteins (IAP) regulates cell death by inhibiting caspases. The region of X-linked (X) IAP containing… (More)
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Highly Cited
1999
Highly Cited
1999
The abundant nuclear enzyme poly(ADP-ribose) polymerase (PARP) synthesizes poly(ADP-ribose) in response to DNA strand breaks… (More)
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Highly Cited
1998
Highly Cited
1998
Inhibitor of apoptosis (IAP) gene products play an evolutionarily conserved role in regulating programmed cell death in diverse… (More)
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Highly Cited
1998
Highly Cited
1998
Caspases plays a key role in the execution phase of apoptosis. "Initiator" caspases, such as caspase-8, activate "effector… (More)
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Highly Cited
1997
Highly Cited
1997
The inhibitor-of-apoptosis (IAP) family of genes has an evolutionarily conserved role in regulating programmed cell death in… (More)
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