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caspase-7

Known as: MCH3, Protease Mch-3, Apoptotic, CMH-1 
A short pro-domain caspase that plays an effector role in APOPTOSIS. It is activated by INITIATOR CASPASES such as CASPASE 3 and CASPASE 10. Several… 
National Institutes of Health

Related topics

Related topics

33 relations
Alzheimer's Disease Pathway KEGGApoptosisCASP2 protein, humanCASP4 protein, human

Broader (1)

Cysteine Endopeptidases

Narrower (1)

Procaspase 7

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
Discovery of a new small-molecule inhibitor of p53-MDM2 interaction using a yeast-based approach.
Highly Cited
2007
Highly Cited
2007
Melanin Concentrating Hormone Is a Novel Regulator of Islet Function and Growth
Melanin concentrating hormone (MCH) is a hypothalamic neuropeptide known to play a critical role in energy balance. We have… 
Highly Cited
2005
Highly Cited
2005
IAPs are functionally non-equivalent and regulate effector caspases through distinct mechanisms
Some members of the inhibitor of apoptosis (IAP) family suppress apoptosis by neutralizing caspases. The current model suggests… 
Highly Cited
2003
Highly Cited
2003
All-trans-retinoic acid-induced apoptosis in human medulloblastoma: activation of caspase-3/poly(ADP-ribose) polymerase 1 pathway.
Current treatments for childhood brain tumor medulloblastoma (MB), radiation and chemotherapy, lead to undesirable side effects… 
Highly Cited
2003
Highly Cited
2003
Role of Caspases, Bid, and p53 in the Apoptotic Response Triggered by Histone Deacetylase Inhibitors Trichostatin-A (TSA) and Suberoylanilide Hydroxamic Acid (SAHA)*
Histone deacetylase activity is potently inhibited by hydroaximc acid derivatives such as suberoylanilide hydroxamic acid (SAHA… 
Highly Cited
2001
Highly Cited
2001
Transtympanic Versus Sustained‐Release Administration of Gentamicin: Kinetics, Morphology, and Function
Objectives/Hypothesis Transtympanic gentamicin therapy has become a popular treatment modality for Meniere's disease, but… 
Highly Cited
1997
Highly Cited
1997
Granule-mediated Killing: Pathways for Granzyme B–initiated Apoptosis
We report that the serine protease granzyme B (GrB), which is crucial for granule-mediated cell killing, initiates apoptosis in… 
Highly Cited
1995
Highly Cited
1995
Effects of live Saccharomyces cerevisiae cells on zoospore germination, growth, and cellulolytic activity of the rumen anaerobic fungus, Neocallimastix frontalis MCH3
The effects of a live yeast strain of Saccharomyces cerevisiae have been investigated on zoospore germination, metabolism, and… 
Highly Cited
1993
Highly Cited
1993
Inhalation of nitric oxide modulates methacholine-induced bronchoconstriction in the rabbit.
Nitric oxide (NO) accounts for the major effects of endothelium-derived relaxing factor. We investigated whether NO, added to the… 
Highly Cited
1985
Highly Cited
1985
Salmonid melanin-concentrating hormone inhibits corticotrophin release.
Melanin-concentrating hormone (MCH) is a neural peptide associated with colour change in fishes. We show here that it also… 
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