caspase-5

Known as: ICH-3 Protease, Cysteine Protease, CASP-5 
Caspase-5 (434 aa, ~50 kDa) is encoded by the human CASP5 gene. This protein is involved in both apoptosis and proteolysis.
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
The murine caspase-11 non-canonical inflammasome responds to various bacterial infections. Caspase-11 activation-induced… (More)
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Highly Cited
2012
Highly Cited
2012
Inflammasomes are multiprotein complexes that include members of the NLR (nucleotide-binding domain leucine-rich repeat… (More)
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Highly Cited
2008
Highly Cited
2008
Computational models of protein structure are usually inaccurate and exhibit significant deviations from the true structure. The… (More)
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Review
2004
Review
2004
Caspases not only play an essential role during apoptotic cell death, but a subfamily of them-the inflammatory caspases-are… (More)
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Highly Cited
2004
Highly Cited
2004
Mutations within the NALP3/cryopyrin/CIAS1 gene are responsible for three autoinflammatory disorders: Muckle-Wells syndrome… (More)
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Highly Cited
2003
Highly Cited
2003
Robetta is a fully automated protein structure prediction server that uses the Rosetta fragment-insertion method. It combines… (More)
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Highly Cited
2002
Highly Cited
2002
Generation of Interleukin (IL)-1beta via cleavage of its proform requires the activity of caspase-1 (and caspase-11 in mice), but… (More)
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Highly Cited
2002
Highly Cited
2002
Caspases belong to a conserved family of cysteinyl aspartate proteinases that are involved in metazoan programmed cell death and… (More)
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Highly Cited
1999
Highly Cited
1999
The majority of tumors from hereditary nonpolyposis colorectal cancer families and a subset of unselected gastrointestinal and… (More)
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Highly Cited
1999
Highly Cited
1999
Interferon gamma (IFNgamma) induces apoptosis in purified human erythroid colony-forming cells (ECFC) and inhibits cell growth… (More)
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