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carebastine

Known as: Benzeneacetic acid, 4-(4-(4-(diphenylmethoxy)-1-piperidinyl)-1-oxobutyl)-alpha,alpha-dimethyl- 
 
National Institutes of Health

Papers overview

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2007
2007
BACKGROUND CC chemokines have been shown to play an important role in inducing selective recruitment of inflammatory cells into… Expand
Highly Cited
2006
Highly Cited
2006
Ebastine undergoes extensive metabolism to form desalkylebastine and hydroxyebastine. Hydroxyebastine is subsequently metabolized… Expand
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Highly Cited
2001
Highly Cited
2001
AIMS Sedation induced by antihistamines is widely recognized to be caused by their penetration through the blood-brain-barrier… Expand
2001
2001
Ebastine (CAS 90729-43-4) is an antiallergic agent which selectively and potently blocks histamine H1-receptors in vivo. A simple… Expand
Review
2000
Review
2000
UNLABELLED Ebastine is a second-generation antihistamine which undergoes transformation to its active metabolite, carebastine… Expand
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2000
2000
Abstract The transport mechanism of the non-sedative Hl-antagonist ebastine and its first-pass car-boxylic acid metabolite… Expand
1998
1998
Ebastine [4'-tert-butyl-4-[4-(diphenylmethoxy)piperidino]butyro phe- none] is a new-generation, nonsedative, H1 antihistamine… Expand
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Highly Cited
1996
Highly Cited
1996
Terfenadine and astemizole belong to the second generation histamine H1 antagonists and are widely prescribed for allergic and… Expand
1994
1994
Pharmacokinetics of ebastine (CAS 90729-43-4), a histamine H1-receptor antagonist, was evaluated in healthy male volunteers. The… Expand
Highly Cited
1988
Highly Cited
1988
1. The kinetics and effects of ebastine 10 and 50 mg were studied after oral dosing in healthy subjects. 2. The parent drug was… Expand