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carebastine
Known as:
Benzeneacetic acid, 4-(4-(4-(diphenylmethoxy)-1-piperidinyl)-1-oxobutyl)-alpha,alpha-dimethyl-
National Institutes of Health
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Related topics
Related topics
4 relations
Broader (4)
Anti-Asthmatic Agents
Butyrophenones
Histamine H1 Antagonists
Piperidines
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2008
Review
2008
Ebastine in allergic rhinitis and chronic idiopathic urticaria
J. Sastre
Allergy
2008
Corpus ID: 12474747
Histamine is a key mediator in the development of allergy symptoms, and oral H1‐antihistamines are among the most widely used…
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Highly Cited
2006
Highly Cited
2006
Characterization of Ebastine, Hydroxyebastine, and Carebastine Metabolism by Human Liver Microsomes and Expressed Cytochrome P450 Enzymes: Major Roles for CYP2J2 and CYP3A
Kwang-Hyeon Liu
,
Mi-Gyung Kim
,
+7 authors
Jae-Gook Shin
Drug Metabolism and Disposition
2006
Corpus ID: 19931009
Ebastine undergoes extensive metabolism to form desalkylebastine and hydroxyebastine. Hydroxyebastine is subsequently metabolized…
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2004
2004
Simultaneous determination of ebastine and its three metabolites in plasma using liquid chromatography-tandem mass spectrometry.
W. Kang
,
Kwang-Hyeon Liu
,
J. Ryu
,
Jae-Gook Shin
Journal of chromatography. B, Analytical…
2004
Corpus ID: 19773422
2000
2000
Blood-Brain Barrier Transport of H1-Antagonist Ebastine and its Metabolite Carebastine
I. Tamai
,
Y. Kido
,
J. Yamashita
,
Y. Sai
,
A. Tsuji
Journal of drug targeting
2000
Corpus ID: 46375269
Abstract The transport mechanism of the non-sedative Hl-antagonist ebastine and its first-pass car-boxylic acid metabolite…
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Review
2000
Review
2000
Ebastine: an update of its use in allergic disorders.
M. Hurst
,
C. Spencer
Drugs
2000
Corpus ID: 195691283
UNLABELLED Ebastine is a second-generation antihistamine which undergoes transformation to its active metabolite, carebastine…
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1999
1999
Anticholinergic effects of desloratadine, the major metabolite of loratadine, in rabbit and guinea-pig iris smooth muscle.
I. Cardelús
,
F. Antón
,
J. Beleta
,
J. Palacios
European journal of pharmacology
1999
Corpus ID: 24437037
1998
1998
Consistency of the efficacy of cetirizine and ebastine on skin reactivity.
N. Frossard
,
M. Mélac
,
O. Benabdesselam
,
G. Pauli
Annals of allergy, asthma & immunology : official…
1998
Corpus ID: 46020008
1997
1997
Comparative effects of nonsedating histamine H1 receptor antagonists, ebastine and terfenadine, on human Kv1.5 channels.
C. Valenzuela
,
E. Delpón
,
L. Franqueza
,
P. Gay
,
J. Vicente
,
J. Tamargo
European journal of pharmacology
1997
Corpus ID: 41542329
1994
1994
Pharmacokinetics of the H1-receptor antagonist ebastine and its active metabolite carebastine in healthy subjects.
T. Yamaguchi
,
T. Hashizume
,
+5 authors
T. Uematsu
Arzneimittel-Forschung
1994
Corpus ID: 29687457
Pharmacokinetics of ebastine (CAS 90729-43-4), a histamine H1-receptor antagonist, was evaluated in healthy male volunteers. The…
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1993
1993
Pharmacokinetics and pharmacodynamics of ebastine in children.
F. Simons
,
W. Watson
,
K. Simons
The Journal of pediatrics
1993
Corpus ID: 37858623
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