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carebastine

Known as: Benzeneacetic acid, 4-(4-(4-(diphenylmethoxy)-1-piperidinyl)-1-oxobutyl)-alpha,alpha-dimethyl- 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (4)

Anti-Asthmatic AgentsButyrophenonesHistamine H1 AntagonistsPiperidines

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2008
Review
2008
Ebastine in allergic rhinitis and chronic idiopathic urticaria
Histamine is a key mediator in the development of allergy symptoms, and oral H1‐antihistamines are among the most widely used… 
Highly Cited
2006
Highly Cited
2006
Characterization of Ebastine, Hydroxyebastine, and Carebastine Metabolism by Human Liver Microsomes and Expressed Cytochrome P450 Enzymes: Major Roles for CYP2J2 and CYP3A
Ebastine undergoes extensive metabolism to form desalkylebastine and hydroxyebastine. Hydroxyebastine is subsequently metabolized… 
2004
2004
Simultaneous determination of ebastine and its three metabolites in plasma using liquid chromatography-tandem mass spectrometry.
2000
2000
Blood-Brain Barrier Transport of H1-Antagonist Ebastine and its Metabolite Carebastine
Abstract The transport mechanism of the non-sedative Hl-antagonist ebastine and its first-pass car-boxylic acid metabolite… 
Review
2000
Review
2000
Ebastine: an update of its use in allergic disorders.
UNLABELLED Ebastine is a second-generation antihistamine which undergoes transformation to its active metabolite, carebastine… 
1999
1999
Anticholinergic effects of desloratadine, the major metabolite of loratadine, in rabbit and guinea-pig iris smooth muscle.
1998
1998
Consistency of the efficacy of cetirizine and ebastine on skin reactivity.
1997
1997
Comparative effects of nonsedating histamine H1 receptor antagonists, ebastine and terfenadine, on human Kv1.5 channels.
1994
1994
Pharmacokinetics of the H1-receptor antagonist ebastine and its active metabolite carebastine in healthy subjects.
Pharmacokinetics of ebastine (CAS 90729-43-4), a histamine H1-receptor antagonist, was evaluated in healthy male volunteers. The… 
1993
1993
Pharmacokinetics and pharmacodynamics of ebastine in children.
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