carbovir

Known as: (+ -)-Carbovir, 2',3'-didehydro-2',3'-dideoxyguanosine 
A nucleoside reverse transcriptase inhibitor analog of guanosine. Carbovir decreases HIV viral loads, retards or prevents the damage to the immune… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1988-2017
051019882017

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Abacavir (ABC) is administered either at 600 mg once daily (ABC 600 mg QD) or 300 mg twice daily (ABC 300 mg BID) in anti-human… (More)
  • figure 1
  • figure 2
Is this relevant?
2007
2007
In this study, the synthesis procedures of 2'-branched carbovir analogues were accomplished. The introduction of a methyl group… (More)
Is this relevant?
Highly Cited
2005
Highly Cited
2005
OBJECTIVE To evaluate the potential for a pharmacologic mechanism to explain suboptimal virologic responses observed in a triple… (More)
Is this relevant?
Highly Cited
2001
Highly Cited
2001
To examine the role of the mitochondrial polymerase (Pol gamma) in clinically observed toxicity of nucleoside analogs used to… (More)
  • figure 1
  • table I
  • figure 2
  • table II
  • figure 3
Is this relevant?
2001
2001
The cyclosaligenyl (cycloSal) derivatives of the monophosphates of three acyclic or carbocyclic guanosine analogues, for example… (More)
Is this relevant?
1992
1992
Two enantiomers of carbovir, a carbocyclic analog of 2',3'-dideoxyguanosine, were compared with respect to their phosphorylation… (More)
  • figure 1
  • table I
  • table IV
  • figure 2
  • figure 4
Is this relevant?
1992
1992
Carbovir (9-[4 alpha-(hydroxymethyl)cyclopent-2-ene-1 alpha-yl]guanine) (CBV) is a carbocyclic analogue of 2',3'-dideoxyguanosine… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • table I
Is this relevant?
1991
1991
Carbovir (the carbocyclic analog of 2'-3'-didehydro-2',3'-dideoxyguanosine) is a potent inhibitor of human immunodeficiency virus… (More)
Is this relevant?
1990
1990
(+-) Carbocyclic 2',3'-didehydro-2',3'-dideoxyguanosine (Carbovir; NSC 614846) is an antiretroviral agent which is undergoing… (More)
Is this relevant?
1988
1988
Carbocyclic 2',3'-didehydro-2',3'-dideoxyguanosine (Carbovir: NSC 614846), a novel nucleoside analog, emerged as a potent and… (More)
Is this relevant?