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carbovir

Known as: (+ -)-Carbovir, 2',3'-didehydro-2',3'-dideoxyguanosine 
A nucleoside reverse transcriptase inhibitor analog of guanosine. Carbovir decreases HIV viral loads, retards or prevents the damage to the immune… 
National Institutes of Health

Papers overview

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Highly Cited
2005
Highly Cited
2005
Objective:To determine the mechanisms of resistance of K65R mutant reverse transcriptase (RT) to the currently approved… 
2001
2001
A new synthesis of cyclobut-A, a carbocyclic nucleoside analogue of oxetanocin is described. The key step involves a… 
2000
2000
A novel, one-pot ring-expansion procedure was developed using Me3S(O)I, NaH, and Sc(OTf)3. The scope and limitations were briefly… 
1999
1999
Stereoselective synthesis of 4'-α-alkylcarbovir derivatives 4 was described based on asymmetric synthesis or a chemoenzymatic… 
Highly Cited
1992
Highly Cited
1992
The synthesis and in vitro anti-HIV activity of two new racemic nucleoside analogues are described; namely, 9-[c-4,t-5-bis… 
1990
1990
Carbovir (CBV) is a highly selective carbocyclic nucleoside inhibitor of HIV replication in human lymphocytes and is potentially… 
1990
1990
We have studied the in vitro effects of carbovir as compared to 3'-azido-3'-deoxythymidine (AZT) on the growth of clonal bone…