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carbovir

Known as: (+ -)-Carbovir, 2',3'-didehydro-2',3'-dideoxyguanosine 
A nucleoside reverse transcriptase inhibitor analog of guanosine. Carbovir decreases HIV viral loads, retards or prevents the damage to the immune… 
National Institutes of Health

Papers overview

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Review
2003
Review
2003
Incorporation of nucleoside analogues by the mitochondrial DNA polymerase has been implicated as the primary cause underlying… 
2002
2002
ABSTRACT Transient kinetic studies with human immunodeficiency virus (HIV) type 1 reverse transcriptase suggest that nucleotide… 
Highly Cited
2002
Highly Cited
2002
ABSTRACT Human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) resistance mutations K65R and M184V result in… 
Highly Cited
2001
Highly Cited
2001
To examine the role of the mitochondrial polymerase (Pol γ) in clinically observed toxicity of nucleoside analogs used to treat… 
Highly Cited
1990
Highly Cited
1990
(+-)-cis-[4-[(2,5-Diamino-6-chloropyrimidinyl)amino]-2- cyclopentenyl]carbinol (5a) was synthesized from 2-amino-4,6… 
Highly Cited
1989
Highly Cited
1989
2',3'-Dideoxyinosine (ddlno) is a potent and selective inhibitor of human immunodeficiency virus in human lymphoid cells and…