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A convenient synthesis of (+)-albicanol based on enzymatic function: total syntheses of (+)-albicanyl acetate, (−)-albicanyl 3,4-dihydroxycinnamate, (−)-drimenol, (−)-drimenin and (−)-ambrox
Abstract By using lipase ‘PL-266’ from Alcaligenes sp. enantioselective acetylation of (±)-albicanol 4 with isopropenyl acetate gave the enantiomerically pure (+)-albicanyl acetate 3 andExpand
Synthesis of Methyl 1-O-(4-Hydroxymethamphetaminyl)-α-D-glucopyranouronate
For the purpose of the direct characterization of the intact conjugated form in the urine of a methamphetamine (MA) abuser, 4-hydroxymethamphetamine (4-OHMA) glucuronate, corresponding to one of theExpand
New total syntheses of (+)-macrosphelides C, F and G
The total synthesis of (+)-macrosphelide C 1 (25% overall yield in nine steps), (+)-macrosphelide F 2 (20% overall yield in nine steps) and (+)-macrosphelide G 3 (22% overall yield in nine steps) hasExpand
Chemoenzymatic synthesis of (+)-totarol, (+)-podototarin, (+)-sempervirol, and (+)-jolkinolides E and D
Abstract The enzymatic resolution products [(1 R ,4a R ,8a R )-1,2,3,4,4a,5,6,7,8,8a-decahydro-5,5,8a-trimethyl-2-oxo- trans -naphthalene-1-methanol-2-ethylene acetal (8a R )- 7 (98% ee) and {acetateExpand
Estimation of optically active methamphetamine and amphetamine using alpha-methoxy-alpha-trifluoromethylphenylacetyl chloride.
A simple analytical method for determination of optically active amphetamine and methamphetamine using (+)-alpha-methoxy-alpha-trifluoromethylphenylacetyl chloride (MTPA-Cl) was developed and the results obtained using the capillary GC method agreed well with those of the NMR method. Expand
Synthesis of naturally occurring β-d-glucopyranoside based on enzymatic β-glycosidation
Abstract For the purpose of synthesis of naturally occurring β- d -glucopyranoside, direct β-glycosidation for seven kinds of the functionalized primary alcohol in the presence of d -glucose usingExpand
Enzymatic hydrolysis in organic solvents for kinetic resolution of water-insoluble α-acyloxy esters with immobilized lipases
Enantioselective hydrolysis of water-insoluble α-acyloxy esters, (±)-5 and (±)-6, was carried out using lipases immobilized with Celite or a synthetic prepolymer (ENTP-4000 or ENT-4000) in aExpand