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capravirine

Known as: (5-(3,5-dichlorophenyl)sulfanyl-4-propan-2-yl-1-(pyridin-4-ylmethyl)imidazol-2-yl)methyl aminoformate, 1H-Imidazole-2-methanol, 5-((3,5-dichlorophenyl)thio)-4-(1-methylethyl)-1-(4-pyridinylmethyl)-, carbamate (ester), 5-((3,5-Dichlorophenyl)thio)-4-isopropyl-1-(4-pyridylmethyl)imidazole-2-methanol Carbamate (ester) 
A non-nucleoside reverse transcriptase inhibitor. Capravirine shows antiviral activity against wild-type HIV as well as HIV strains with mutations in… 
National Institutes of Health

Papers overview

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2009
2009
A major problem associated with non-nucleoside reverse transcriptase inhibitors (NNRTIs) for the treatment of HIV is their lack… 
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Review
2004
Review
2004
  • J. Balzarini
  • Current topics in medicinal chemistry
  • 2004
  • Corpus ID: 42897031
Almost fifteen years ago, the first non-nucleoside reverse transcriptase (RT) inhibitor (NNRTI) lead compounds have been… 
2004
2004
Metabolism and disposition of capravirine, a new non-nucleoside reverse transcriptase inhibitor, were studied in healthy male… 
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Review
2004
Review
2004
Non-nucleoside reverse transcriptase (RT) inhibitors (NNRTIs) have become an inherent ingredient of the drug combination schemes… 
2004
2004
Capravirine is a nonnucleoside reverse-transcriptase inhibitor (NNRTI) with a unique resistance profile. Although single… 
Review
2001
Review
2001
  • E. De Clercq
  • Current medicinal chemistry
  • 2001
  • Corpus ID: 23439270
Virtually all the compounds that are currently used, or under advanced clinical trial, for the treatment of HIV infections… 
Highly Cited
2001
Highly Cited
2001
  • E. De Clercq
  • Journal of clinical virology : the official…
  • 2001
  • Corpus ID: 37871480