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candoxatril

Known as: 3-(1-((4-carboxycyclohexyl)carbamoyl)cyclopentyl)-2-(2-methoxyethoxymethyl)propanoic acid 5-indanyl ester 
National Institutes of Health

Related topics

Related topics

5 relations

Broader (4)

Antihypertensive AgentsIndansPropionatesProtease Inhibitors

Narrower (1)

UK 79300

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Role of the effect of inhibition of neutral endopeptidase on vascular and neural complications in streptozotocin-induced diabetic rats.
2001
2001
Omapatrilat, a dual angiotensin-converting enzyme and neutral endopeptidase inhibitor, prevents fatty streak deposit in apolipoprotein E-deficient mice.
2001
2001
Potentiation of urinary atrial natriuretic peptide interferes with macula densa function.
2000
2000
Modulation of functionally active endothelin-converting enzyme by chronic neutral endopeptidase inhibition in experimental atherosclerosis.
BACKGROUND Endothelin-converting enzyme-1 (ECE-1) processes big endothelin-1 (ET-1) to ET-1, a peptide implicated in atheroma… 
1999
1999
Me-DuPHOS-Rh-Catalyzed Asymmetric Synthesis of the Pivotal Glutarate Intermediate for Candoxatril.
A greatly improved process has been developed for synthesis of the glutarate derivative 2, a key intermediate required for Pfizer… 
1998
1998
Candoxatril improves exercise capacity in patients with chronic heart failure receiving angiotensin converting enzyme inhibition.
AIMS To assess the effect of candoxatril, a novel neutral endopeptidase inhibitor, on exercise capacity, clinical status and… 
Highly Cited
1995
Highly Cited
1995
The role of neutral endopeptidase in dogs with evolving congestive heart failure.
BACKGROUND Recent studies suggest that neurohumoral mechanisms including decreased renal responses to increases in atrial… 
1994
1994
Evidence for a new role of natriuretic peptides: control of intraocular pressure.
To study the possible physiological role of atrial natriuretic peptide (ANP) in the regulation of intraocular pressure (IOP) the… 
1992
1992
Characterization of atrial natriuretic peptide in urine from rats treated with a neutral endopeptidase inhibitor.
1991
1991
Dietary Sodium and Inhibition of Neutral Endopeptidase 24.11 in Essential Hypertension
Basal atrial natriuretic peptide levels and the response to exogenous atrial natriuretic peptide are influenced by dietary sodium… 
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