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Ghrelin is a growth-hormone-releasing acylated peptide from stomach
Small synthetic molecules called growth-hormone secretagogues (GHSs) stimulate the release of growth hormone (GH) from the pituitary. They act through GHS-R, a G-protein-coupled receptor for whichExpand
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A role for ghrelin in the central regulation of feeding
Ghrelin is an acylated peptide that stimulates the release of growth hormone from the pituitary. Ghrelin-producing neurons are located in the hypothalamus, whereas ghrelin receptors are expressed inExpand
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Adrenomedullin: a novel hypotensive peptide isolated from human pheochromocytoma.
A novel hypotensive peptide was discovered in human pheochromocytoma by monitoring the elevating activity of platelet cAMP. Since this peptide is abundant in normal adrenal medulla as well as inExpand
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A new natriuretic peptide in porcine brain
Atrial natriuretic peptide (ANP), a hormone secreted from mammalian atria, regulates the homoeostatic balance of body fluid and blood pressure1–3. ANP-like immunoreactivity is also present in theExpand
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The role of the gastric afferent vagal nerve in ghrelin-induced feeding and growth hormone secretion in rats.
BACKGROUND & AIMS Visceral sensory information is transmitted to the brain through the afferent vagus nerve. Ghrelin, a peptide primarily produced in the stomach, stimulates both feeding and growthExpand
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C-type natriuretic peptide (CNP): a new member of natriuretic peptide family identified in porcine brain.
Two types of natriuretic peptide, atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP), very similar to each other in structure and in pharmacological effect, are known to be presentExpand
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Ghrelin and des-acyl ghrelin: two major forms of rat ghrelin peptide in gastrointestinal tissue.
Ghrelin, a novel peptide purified from stomach, is the endogenous ligand for the growth hormone secretagogue receptor and has potent growth hormone-releasing activity. The Ser3 residue of ghrelin isExpand
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Primary structure and functional expression from complementary DNA of the rod photoreceptor cyclic GMP-gated channel
The complete amino-acid sequence of the cyclic GMP-gated channel from bovine retinal rod photo-receptors, deduced by cloning and sequencing its complementary DNA, shows that the protein containsExpand
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Cloning and characterization of cDNA encoding a precursor for human adrenomedullin.
Adrenomedullin is a novel hypotensive peptide recently isolated from human pheochromocytoma. Since a high concentration of immunoreactive adrenomedullin was found in pheochromocytoma tissue, the cDNAExpand
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Human L-type amino acid transporter 1 (LAT1): characterization of function and expression in tumor cell lines.
System L is a major nutrient transport system responsible for the transport of large neutral amino acids including several essential amino acids. We previously identified a transporter (L-type aminoExpand
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