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Ghrelin is a growth-hormone-releasing acylated peptide from stomach
The occurrence of ghrelin in both rat and human indicates that GH release from the pituitary may be regulated not only by hypothalamic GHRH, but also by ghrelIn, a peptide specifically releases GH both in vivo and in vitro.
A role for ghrelin in the central regulation of feeding
It is shown that ghrelin is involved in the hypothalamic regulation of energy homeostasis and probably has a function in growth regulation by stimulating feeding and release of growth hormone.
Adrenomedullin: a novel hypotensive peptide isolated from human pheochromocytoma.
Occurrence of adrenomedullin indicates the possible existence of a novel system for circulation control and suggests that adrenomed Mullin is a new hormone participating in blood pressure control.
A new natriuretic peptide in porcine brain
Atrial natriuretic peptide (ANP), a hormone secreted from mammalian atria, regulates the homoeostatic balance of body fluid and blood pressure13. ANP-like immunoreactivity is also present in the…
The role of the gastric afferent vagal nerve in ghrelin-induced feeding and growth hormone secretion in rats.
This study indicated that the gastric vagal afferent is the major pathway conveying ghrelin's signals for starvation and GH secretion to the brain.
C-type natriuretic peptide (CNP): a new member of natriuretic peptide family identified in porcine brain.
Selective activation of the B natriuretic peptide receptor by C-type natriuretic peptide (CNP).
A member of this hormone family, C-type natriuretic peptide (CNP), potently and selectively activated the human ANPR-B guanylyl cyclase, and may be involved in the regulation of fluid homeostasis by the central nervous system.
Primary structure and functional expression from complementary DNA of the rod photoreceptor cyclic GMP-gated channel
The complete amino-acid sequence of the cyclic GMP-gated channel from bovine retinal rod photo-receptors, deduced by cloning and sequencing its complementary DNA, shows that the protein contains…
Ghrelin and des-acyl ghrelin: two major forms of rat ghrelin peptide in gastrointestinal tissue.
- H. Hosoda, M. Kojima, H. Matsuo, K. Kangawa
- BiologyBiochemical and biophysical research…
- 29 December 2000
While gh Relin activates growth-hormone secretagogue (GHS) receptor-expressing cells, the nonmodified des-n-octanyl form of ghrelin, designated as des-acyl ghrel in, does not.