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calcitroic acid
Known as:
1alpha-Hydroxy-23-Carboxytetranorvitamin D
, 24-Nor-9,10-Secochola-5,7,10(19)-Trien-23-Oic Acid, 1,3-Dihydroxy-, (1alpha,3beta,5Z,7E)-
, 1alpha,3beta-Dihydroxy-24-Nor-9,10-Seco-5,7,10(19)-Cholatrien-23-Oic Acid
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A metabolite of calcidiol that is produced by 1,25-dihydroxyvitamin D3 24-hydroxylase (CYP24A1).
National Institutes of Health
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Related topics
Related topics
2 relations
Broader (1)
Calcitriol
analogs & derivatives
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Synthesis of Calcitroic Acid to Determine its Potential for Prevention of Colon Cancer
Viktoriia Senych
2017
Corpus ID: 91015822
2016
2016
Maternal hypercalcaemia due to CYP24A1 loss of function mutations
T. Upton
,
C. Florkowski
,
I. Phillips
,
P. Hunt
2016
Corpus ID: 89321447
References Schlingmann et al. (2011). Mutations in CYP24A1 and idiopathic infantile hypercalcemia. New Engl. J. Med. http://doi…
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2011
2011
ANABOLIC VITAMIN D25-HYDROXYLASE ACTIVITY INTO THE HUMAN VITAMIN D CATABOLIC ENZYME , CYTOCHROME P 450 CYP 24 A 1 , BY A V 391 L MUTATION
M. Kaufmann
,
D. Prosser
,
Glenville Jones
2011
Corpus ID: 26782883
CYP24A1 is a mitochondrial cytochrome P450 (CYP) that catabolizes 1α,25-dihydroxyvitamin D3 (1α,25-(OH)2D3) to different products…
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2002
2002
Rat Cytochrome P 450 C 24 ( CYP 24 ) Does Not Metabolize 1 , 25-Dihydroxyvitamin D 2 to Calcitroic Acid
R. Horst
,
J. Omdahl
,
S. Reddy
2002
Corpus ID: 44923075
1a-Hydroxy-23 carboxy-24,25,26,27-tetranorvitaminD3 (calcitroic acid) is known to be themajorwatersolublemetabolite…
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Highly Cited
1987
Highly Cited
1987
Isolation and identification of 1,23-dihydroxy-24,25,26,27-tetranorvitamin D3, a new metabolite of 1,25-dihydroxyvitamin D3 produced in rat kidney.
G. Reddy
,
K. Tserng
,
B. R. Thomas
,
R. Dayal
,
A. Norman
Biochemistry
1987
Corpus ID: 36958918
A new metabolite of vitamin D3 was produced in vitro by perfusing rat kidneys with 1,25-dihydroxyvitamin D3 (4 X 10(-6) M). It…
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1987
1987
Conjugated forms of [3H] alpha, 25-dihydroxyvitamin D3 in rat bile.
B. Ayton
,
F. Martin
Journal of Steroid Biochemistry
1987
Corpus ID: 31355467
When small doses of [3H]D3, [3H]25-OHD3 and [3H]alpha, 25-diOHD3 were administered intravenously to rats 6.3 +/- 1.1% (means…
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1984
1984
1 alpha, 25-Dihydroxyvitamin D3 specifically induces its own metabolism in a human cancer cell line.
J. Eisman
,
E. Sher
,
L. Suva
,
R. Frampton
,
F. Mclean
Endocrinology
1984
Corpus ID: 20048974
Human breast cancer and malignant melanoma cells possess specific, high affinity receptors for 1 alpha,25-dihydroxyvitamin D3 (1…
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