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calcitroic acid

Known as: 1alpha-Hydroxy-23-Carboxytetranorvitamin D, 24-Nor-9,10-Secochola-5,7,10(19)-Trien-23-Oic Acid, 1,3-Dihydroxy-, (1alpha,3beta,5Z,7E)-, 1alpha,3beta-Dihydroxy-24-Nor-9,10-Seco-5,7,10(19)-Cholatrien-23-Oic Acid 
A metabolite of calcidiol that is produced by 1,25-dihydroxyvitamin D3 24-hydroxylase (CYP24A1).
National Institutes of Health

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2 relations

Broader (1)

Calcitriol
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Metabolic stability of 3‐Epi‐1α,25‐dihydroxyvitamin D3 over 1α, 25‐dihydroxyvitamin D3: Metabolism and molecular docking studies using rat CYP24A1
3‐epi‐1α,25‐dihydroxyvitamin D3 (3‐epi‐1α,25(OH)2D3), a natural metabolite of 1α,25‐dihydroxyvitamin D3 (1α,25(OH)2D3), exhibits… 
2007
2007
Removal of C-ring from the CD-ring skeleton of 1alpha,25-dihydroxyvitamin D3 does not alter its target tissue metabolism significantly.
2006
2006
23-carboxy-24,25,26,27-tetranorvitamin D3 (calcioic acid) and 24-carboxy-25,26,27-trinorvitamin D3 (cholacalcioic acid): end products of 25-hydroxyvitamin D3 metabolism in rat kidney through C-24…
2003
2003
Rat cytochrome P450C24 (CYP24) does not metabolize 1,25‐dihydroxyvitamin D2 to calcitroic acid
1α‐Hydroxy‐23 carboxy‐24,25,26,27‐tetranorvitamin D3 (calcitroic acid) is known to be the major water‐soluble metabolite produced… 
2001
2001
Calcitroic acid is a major catabolic metabolite in the metabolism of 1 alpha-dihydroxyvitamin D(2).
Calcitroic acid (1 alpha-hydroxy-23 carboxy-24,25,26,27-tetranorvitamin D(3)) is known to be the major water-soluble metabolite… 
2001
2001
Double bond in the side chain of 1α,25-dihydroxy-22-ene-vitamin D3 is reduced during its metabolism: studies in chronic myeloid leukemia (RWLeu-4) cells and rat kidney
Highly Cited
1999
Highly Cited
1999
Production of 1alpha,25-dihydroxy-3-epi-vitamin D3 in two rat osteosarcoma cell lines (UMR 106 and ROS 17/2.8): existence of the C-3 epimerization pathway in ROS 17/2.8 cells in which the C-24…
1992
1992
Normal 24-hydroxylation of vitamin D metabolites in patients with vitamin D-dependency rickets type I. Structural implications for the vitamin D hydroxylases.
The steady state serum concentration of 1,25-dihydroxyvitamin D [1,25-(OH)2D] is determined by the relative rates of its… 
Highly Cited
1987
Highly Cited
1987
Isolation and identification of 1,23-dihydroxy-24,25,26,27-tetranorvitamin D3, a new metabolite of 1,25-dihydroxyvitamin D3 produced in rat kidney.
A new metabolite of vitamin D3 was produced in vitro by perfusing rat kidneys with 1,25-dihydroxyvitamin D3 (4 X 10(-6) M). It… 
1983
1983
Monoclonal antibody with high affinity for 1,25-dihydroxycholecalciferol.
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