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butazidamine

Known as: 3H-Pyrazol-3-one, 4-butyl-1,2-dihydro-5-hydroxy-1,2-diphenyl-, compd. with 3-(3-(dimethylamino)propoxy)-1-(phenylmethyl)-1H-indazole (1:1), 4-butyl-1,2-diphenyl-5-hydroxy-3-oxo-pyrazolidine compd. with 1-benzyl-3,3-(dimethylamino)propoxy-1H-indazole 
National Institutes of Health

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2 relations

Broader (1)

Phenylbutazone
analogs & derivatives

Papers overview

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2017
2017
From PIM1 to PI3Kδ via GSK3β: Target Hopping through the Kinome.
Selective inhibitors of phosphoinositide 3-kinase delta are of interest for the treatment of inflammatory diseases. Initial… 
2009
2009
X-ray structures of aza-proline-containing peptides.
The aza-analogue of proline (AzPro) contains a nitrogen atom in place of the CH alpha of the cognate residue. The resolution of… 
2005
2005
Discovery of novel conformationally restricted diazocan peptidomimetics as inhibitors of interleukin-1beta synthesis.
A novel diazocan containing dipeptide mimetic was synthesized via reductive N-N bond cleavage of a pyrazolidino-pyrazolidine… 
2004
2004
3,5 disubstituted indazole compounds, pharmaceutical compositions, and methods for mediating or inhibiting cell proliferation
3,5 disubstituted indazole compounds that modulate and/or inhibit cell proliferation, such as the activity of protein kinases are… 
2003
2003
NOS inhibitors exhibit antinociceptive properties in the rat formalin test
PurposeTo assess the systemic and nociceptive effects of nitric oxide synthase (NOS) inhibitors in the modulation of acute pain… 
2003
2003
Synthesis, Pharmacological Study and Modeling of 7-Methoxyindazole and Related Substituted Indazoles as Neuronal Nitric Oxide Synthase Inhibitors
The synthesis, pharmacological evaluation and modelisation of 7-methoxyindazole (7-MI) and related alkoxy-indazoles as novel… 
1998
1998
Azaproline as a beta-turn-inducer residue opposed to proline.
Azaproline (AzPro) is an analogue of proline containing a nitrogen atom in place of the C(alpha)H group. AzPro has been… 
1995
1995
Effect of 7‐nitro indazole on quinolinic acid‐induced striatal toxicity in the rat
Nitric oxide (NO) is implicated as a mediator of cell death in models of neurodegenerative disease. However, the precise role of… 
1994
1994
Potentiation of NMDA-mediated toxicity on nigrostriatal neurons by a low dose of 7-nitro indazole
1980
1980
New metabolites of sulfinpyrazone in man.
The disposition and metabolism of sulfinpyrazone have been studied after oral administration of 100 mg 14C-labelled drug to two… 
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