Phenylbutazone

Known as: 3,5-Dioxo-1,2-diphenyl-4-n-butylpyrazolidine, Diphenylbutazone, Phenylbutazon 
A butyl-diphenyl-pyrazolidinedione that has anti-inflammatory, antipyretic, and analgesic activities. It has been used in ANKYLOSING SPONDYLITIS… (More)

Topic mentions per year

Topic mentions per year

1950-2017
05010019502016

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Relatively few selective substrate and inhibitor probes have been identified for human UDP-glucuronosyltransferases (UGTs). This… (More)
  • table 1
  • table 2
  • figure 1
  • figure 2
  • table 3
Is this relevant?
2005
2005
We report on the inhibitory activity of the NSAIDs meloxicam, carprofen, phenylbutazone and flunixin, on blood cyclooxygenases in… (More)
Is this relevant?
Highly Cited
1994
Highly Cited
1994
We developed an in vitro expression system for accurate kinetic analyses of the inhibition of the human prostaglandin H synthase… (More)
Is this relevant?
1993
1993
The relative toxicity of phenylbutazone, flunixin meglumine, and ketoprofen was studied in healthy adult horses. Sixteen horses… (More)
Is this relevant?
Highly Cited
1990
Highly Cited
1990
In previous papers we demonstrated that cyclosporin A (CsA) was specifically oxidized in rabbit and human liver by cytochrome P… (More)
Is this relevant?
Highly Cited
1986
Highly Cited
1986
A new model for evaluating nonsteroidal anti-inflammatory drugs (NSAIDs) is described. In this model of postoperative… (More)
Is this relevant?
1979
1979
The oral administration of phenylbutazone at a dose rate of approximately 10 mg per kg per day for seven to 14 days resulted in… (More)
Is this relevant?
1976
1976
Does phenylbutazone exert an inhibitory influence on the progression of ossification of the lumbar vertebral column? In a… (More)
Is this relevant?
1974
1974
An examination of the metabolic fate of the R and the S isomers of warfarin revealed that the two isomers were metabolized by… (More)
  • figure 1
  • figure 2
  • table I
  • table I
  • figure 3
Is this relevant?
1970
1970
The purposes of the present investigation were to assess the genetic contribution to thevariability between individuals in the… (More)
Is this relevant?