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Phenylbutazone

Known as: 3,5-Dioxo-1,2-diphenyl-4-n-butylpyrazolidine, Diphenylbutazone, Phenylbutazon 
A butyl-diphenyl-pyrazolidinedione that has anti-inflammatory, antipyretic, and analgesic activities. It has been used in ANKYLOSING SPONDYLITIS… Expand
National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
Relatively few selective substrate and inhibitor probes have been identified for human UDP-glucuronosyltransferases (UGTs). This… Expand
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Review
1998
Review
1998
Accumulating evidence indicates that CYP2C9 ranks amongst the most important drug metabolizing enzymes in humans. Substrates for… Expand
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Highly Cited
1993
Highly Cited
1993
The relative toxicity of phenylbutazone, flunixin meglumine, and ketoprofen was studied in healthy adult horses. Sixteen horses… Expand
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Highly Cited
1990
Highly Cited
1990
In previous papers we demonstrated that cyclosporin A (CsA) was specifically oxidized in rabbit and human liver by cytochrome P… Expand
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Highly Cited
1986
Highly Cited
1986
A new model for evaluating nonsteroidal anti-inflammatory drugs (NSAIDs) is described. In this model of postoperative… Expand
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Highly Cited
1974
Highly Cited
1974
An examination of the metabolic fate of the R and the S isomers of warfarin revealed that the two isomers were metabolized by… Expand
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Highly Cited
1973
Highly Cited
1973
Some pharmacological actions of curcumin (diferuloyl methane) have been examined in rats, mice and cats. The compound possesses… Expand
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Highly Cited
1968
Highly Cited
1968
The interaction of clinically established anti-inflammatory drugs with some proteins has shown these drugs to strongly inhibit… Expand
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Highly Cited
1962
Highly Cited
1962
Summary A method is presented for measuring the edema induced by injection of 0.05 ml of 1% solution of carrageenin, an extract… Expand
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1959
1959
of a salicylate metabolite, gentisic acid. The re- lationships between the renal excretion of salicyl- ate and of urate are then… Expand
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