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brotizolam

Known as: 2-bromo-4-(2-chlorophenyl)-9-methyl-6H-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepine, Brotizolamum, 6H-Thieno(3,2-F)(1,2,4)Triazolo(4,3-A)(1,4)Diazepine,2-Bromo-4-(2-Chlorophenyl)-9-Methyl- 
A triazolo-benzodiazepine derivative with sedative, hypnotic, anxiolytic and anticonvulsant activities. Brotizolam binds to the benzodiazepine… 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (2)

AzepinesHypnotics and Sedatives

Narrower (2)

LendorminWe 941

Papers overview

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1986
1986
Kinetic and dynamic interaction of brotizolam and ethanol.
Thirteen healthy male volunteers ingested a single 0.25 mg dose of the thienodiazepine hypnotic, brotizolam, on two occasions… 
1986
1986
General pharmacology of brotizolam in animals.
Brotizolam (2-bromo-4-(2-chlorophenyl)-9-methyl-6H-thieno[3,2-f]-1,2,4-triazolo [4,3-a]-1,4-diazepine, We 941, Lendormin) is a… 
1985
1985
Brotizolam radioimmunoassay: development, evaluation, and application to human plasma samples.
A radioimmunoassay for the determination of the hypnotic agent brotizolam (11) was developed. With this procedure, an antiserum… 
1984
1984
Low doses of brotizolam and nitrazepam as hypnotics in the elderly.
0.125 mg brotizolam and 2.5 mg nitrazepam proved to be equipotent in promoting and maintaining sleep in 29 elderly patients used… 
1983
1983
Pharmacokinetics of brotizolam in the elderly.
Disposition of brotizolam in patients aged 71-93 years was compared with that of healthy young subjects aged 21-26 years. The… 
1983
1983
Pharmacokinetics of oral brotizolam in patients with liver cirrhosis.
Disposition of oral brotizolam (0.5 mg) was studied in male patients with liver cirrhosis (patients) and in other patients… 
1983
1983
Pharmacokinetics of brotizolam in healthy subjects following intravenous and oral administration.
Pharmacokinetics and bioavailability of brotizolam after i.v. and oral administration were studied in healthy young volunteers… 
1983
1983
Effects of brotizolam on the sleep of chronic insomniacs.
Effects of 0.5 mg brotizolam on the sleep of chronic insomniacs were assessed electroencephalographically and subjectively over… 
1983
1983
Pharmacokinetics and metabolism of brotizolam in animals.
Distribution, and excretion of [14C]-brotizolam were determined after oral and intravenous administration in the rat, dog, rhesus… 
1983
1983
Quantitative pharmaco-EEG and performance after administration of brotizolam to healthy volunteers.
The activity of brotizolam (0.1, 0.3 and 0.5 mg) was studied in normal subjects using quantitative pharmaco-EEG, psychometric and… 
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