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Blood levels and electroencephalographic effects of diazepam and bromazepam
- M. Fink, P. Irwin, R. Weinfeld, M. A. Schwartz, A. H. Canney
- Psychology, MedicineClinical pharmacology and therapeutics
- 1 August 1976
Although a weakly significant correlation was found between measurable diazepam blood levels and amount of increased EEG beta activity, the relationship between measurable bromazepamBlood levels and the degree of EEG changes was not significant.
Rivastigmine in Alzheimer disease: efficacy over two years.
- G. Grossberg, P. Irwin, A. Satlin, P. Mesenbrink, R. Spiegel
- Medicine, PsychologyThe American journal of geriatric psychiatry…
- 1 July 2004
Rivastigmine had a beneficial effect on cognitive performance for up to 2 years in patients with AD, versus no treatment or placebo treatment in historical-control subjects and remained safe over this 2-year treatment period.
Greater brain response of left-handers to drugs
- P. Irwin
- Psychology, BiologyNeuropsychologia
- 31 December 1985
Pharmacoelectroencephalographic study of brotizolam, a novel hypnotic
The effects on the quantitative EEG and behavior of two doses (0.1 and 0.3 mg) of the novel sedative compound brotizolam were compared to those of 10 mg flurazepam and placebo in a crossover study in…
Spectral difference index: a single EEG measure of drug effect.
- P. Irwin
- PsychologyElectroencephalography and clinical…
- 1 September 1982
Determination of the central effects of the asthma prophylactic ketotifen, the bronchodilator theophylline, and both in combination: an application of quantitative electroencephalography to the study…
- M. Matejcek, P. Irwin, G. Neff, K. Abt, W. Wehrli
- Medicine, BiologyInternational journal of clinical pharmacology…
- 1 May 1985
Findings suggest a mutual attenuation of the CNS effects of ketotifen and theophylline at therapeutic doses and encourage their combined use in asthma therapy.
Neuroendocrine measures in psychiatric patients: Course and outcome with ECT
Clinical study of mianserin, imipramine and placebo in depression: blood level and MHPG correlations.
- G. F. Perry, B. Fitzsimmons, L. Shapiro, P. Irwin
- Psychology, MedicineBritish journal of clinical pharmacology
- 1 February 1978
1. The clinical efficacy of mianserin, a tetracyclic compound, was compared with imipramine and placebo in 47 hospitalized depressed patients. 2. The clinical ratings showed that the three treatment…
Safety/tolerability trial of SDZ ENA 713 in patients with probable Alzheimer's disease.
CNS effects of the antihistamines diphenhydramine and terfenadine (RMI 9918).
The quantitative EEG profile of a putative antihistaminic drug, terfenadine, was determined in a crossover comparison with diphenhydramine in normal male volunteers and confirmed the lack of CNS effect observed in preclinical and clinical trials.