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bromopyruvate

Known as: 3-bromopyruvate 
 
National Institutes of Health

Papers overview

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Review
2019
Review
2019
Tumor formation and growth depend on various biological metabolism processes that are distinctly different with normal tissues… Expand
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Highly Cited
2012
Highly Cited
2012
The small alkylating molecule, 3-bromopyruvate (3BP), is a potent and specific anticancer agent. 3BP is different in its action… Expand
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Highly Cited
2010
Highly Cited
2010
BACKGROUND Autophagy, a cellular response to stress, plays a role in resistance to chemotherapy in cancer cells. Resistance… Expand
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Highly Cited
2009
Highly Cited
2009
Desperately Seeking Glucose Mutations in oncogenes and tumor suppressor genes allow cancer cells to outgrow their neighboring… Expand
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Highly Cited
2009
Highly Cited
2009
3-BrPA (3-bromopyruvate) is an alkylating agent with anti-tumoral activity on hepatocellular carcinoma. This compound inhibits… Expand
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Highly Cited
2009
Highly Cited
2009
It has long been observed that cancer cells rely more on glycolysis to generate ATP and actively use certain glycolytic metabolic… Expand
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Highly Cited
2009
Highly Cited
2009
BACKGROUND The pyruvic acid analog 3-bromopyruvate (3BrPA) is an alkylating agent known to induce cancer cell death by blocking… Expand
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Review
2006
Review
2006
A key hallmark of many cancers, particularly the most aggressive, is the capacity to metabolize glucose at an elevated rate, a… Expand
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Highly Cited
2004
Highly Cited
2004
A common feature of many advanced cancers is their enhanced capacity to metabolize glucose to lactic acid. In a challenging study… Expand
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Highly Cited
2001
Highly Cited
2001
The rabbit VX2 tumor when implanted in the liver has proven convenient as a model for studying hepatocellular carcinomas. However… Expand
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