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Pyruvates

Known as: Pyruvates [Chemical/Ingredient], pyruvate 
Derivatives of PYRUVIC ACID, including its salts and esters.
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Metabolic dysfunction is a well-established feature of Alzheimer's disease (AD), evidenced by brain glucose hypometabolism that… Expand
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Review
2016
Review
2016
More than two hundred years after its discovery, lactate still remains an intriguing molecule. Considered for a long time as a… Expand
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Review
2015
Review
2015
Most tumor cells show different metabolic pathways than normal cells. Even under the conditions of sufficient oxygen, they… Expand
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Review
2015
Review
2015
BACKGROUND In cancer cells, metabolism is shifted to aerobic glycolysis with lactate production coupled with a higher uptake of… Expand
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Highly Cited
2011
Highly Cited
2011
Control of intracellular reactive oxygen species (ROS) concentrations is critical for cancer cell survival. We show that, in… Expand
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Highly Cited
2008
Highly Cited
2008
Growth factors stimulate cells to take up excess nutrients and to use them for anabolic processes. The biochemical mechanism by… Expand
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Highly Cited
2007
Highly Cited
2007
Tumor cell proliferation requires rapid synthesis of macromolecules including lipids, proteins, and nucleotides. Many tumor cells… Expand
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Highly Cited
2006
Highly Cited
2006
Activation of glycolytic genes by HIF-1 is considered critical for metabolic adaptation to hypoxia through increased conversion… Expand
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Review
2005
Review
2005
Proliferating cells and tumor cells in particular express the pyruvate kinase isoenzyme type M2 (M2-PK). Within the tumor… Expand
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Highly Cited
2002
Highly Cited
2002
Quantitative proteomics has traditionally been performed by two-dimensional gel electrophoresis, but recently, mass spectrometric… Expand
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