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brain renin-angiotensin system

The process in which an angiotensin-mediated signaling system present in the brain regulates the force with which blood passes through the… Expand
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Brain-Selective Overexpression of Human Angiotensin-Converting Enzyme Type 2 Attenuates Neurogenic Hypertension
Rationale: Angiotensin converting enzyme type 2 (ACE2) is a new member of the brain renin-angiotensin system, that might be… Expand
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Highly Cited
2010
Highly Cited
2010
Involvement of the Brain (Pro)renin Receptor in Cardiovascular Homeostasis
Rationale: Despite overwhelming evidence of the importance of brain renin–angiotensin system (RAS), the very existence of… Expand
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Highly Cited
2009
Highly Cited
2009
Brain nuclear factor-kappa B activation contributes to neurohumoral excitation in angiotensin II-induced hypertension.
AIMS Angiotensin II (ANG II)-induced inflammatory and oxidative stress responses contribute to the pathogenesis of hypertension… Expand
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Highly Cited
2009
Highly Cited
2009
Continuous Activation of Renin-Angiotensin System Impairs Cognitive Function in Renin/Angiotensinogen Transgenic Mice
We examined the possibility that continuous activation of the human brain renin-angiotensin system causes cognitive impairment… Expand
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Highly Cited
2007
Highly Cited
2007
Differential expression of neuronal ACE2 in transgenic mice with overexpression of the brain renin-angiotensin system.
Angiotensin-converting enzyme 2 (ACE2) is a newly discovered carboxy-peptidase responsible for the formation of vasodilatory… Expand
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Review
2003
Review
2003
The brain renin-angiotensin system: location and physiological roles.
Angiotensinogen, the precursor molecule for angiotensins I, II and III, and the enzymes renin, angiotensin-converting enzyme (ACE… Expand
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Highly Cited
2001
Highly Cited
2001
Cortical alterations of angiotensin converting enzyme, angiotensin II and AT1 receptor in Alzheimer’s dementia
We investigated the immunohistochemical alterations of angiotensin converting enzyme (ACE), angiotensin II and AT1 receptor in… Expand
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Highly Cited
1998
Highly Cited
1998
The brain renin-angiotensin system contributes to the hypertension in mice containing both the human renin and human angiotensinogen transgenes.
We have previously shown that mice transgenic for both the human renin and human angiotensinogen genes (RA+) exhibit appropriate… Expand
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Highly Cited
1996
Highly Cited
1996
Identification of metabolic pathways of brain angiotensin II and III using specific aminopeptidase inhibitors: predominant role of angiotensin III in the control of vasopressin release.
Angiotensin (Ang) II and Ang III are two peptide effectors of the brain renin-angiotensin system that participate in the control… Expand
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Highly Cited
1992
Highly Cited
1992
The brain renin-angiotensin system: localization and general significance.
This report summarizes the present data about the existence of components of the renin-angiotensin system in the rat brain… Expand
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