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brain renin-angiotensin system

The process in which an angiotensin-mediated signaling system present in the brain regulates the force with which blood passes through the… Expand
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Brain nuclear factor-kappa B activation contributes to neurohumoral excitation in angiotensin II-induced hypertension.
AIMS Angiotensin II (ANG II)-induced inflammatory and oxidative stress responses contribute to the pathogenesis of hypertension… Expand
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Highly Cited
2007
Highly Cited
2007
Differential expression of neuronal ACE2 in transgenic mice with overexpression of the brain renin-angiotensin system.
Angiotensin-converting enzyme 2 (ACE2) is a newly discovered carboxy-peptidase responsible for the formation of vasodilatory… Expand
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Review
2003
Review
2003
The brain renin-angiotensin system: location and physiological roles.
Angiotensinogen, the precursor molecule for angiotensins I, II and III, and the enzymes renin, angiotensin-converting enzyme (ACE… Expand
Review
2003
Review
2003
Brain renin–angiotensin system dysfunction in hypertension: recent advances and perspectives
This review focuses on the dysfunction of the intrinsic brain renin–angiotensin system (RAS) in the pathogenesis of hypertension… Expand
Highly Cited
1998
Highly Cited
1998
The brain renin-angiotensin system contributes to the hypertension in mice containing both the human renin and human angiotensinogen transgenes.
We have previously shown that mice transgenic for both the human renin and human angiotensinogen genes (RA+) exhibit appropriate… Expand
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Review
1997
Review
1997
Important roles for angiotensin III and IV in the brain renin-angiotensin system
Considerable evidence now suggests that the precursors and enzymes necessary for the formation and degradation of biologically… Expand
Highly Cited
1996
Highly Cited
1996
Identification of metabolic pathways of brain angiotensin II and III using specific aminopeptidase inhibitors: predominant role of angiotensin III in the control of vasopressin release.
Angiotensin (Ang) II and Ang III are two peptide effectors of the brain renin-angiotensin system that participate in the control… Expand
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Highly Cited
1992
Highly Cited
1992
The brain renin-angiotensin system: localization and general significance.
This report summarizes the present data about the existence of components of the renin-angiotensin system in the rat brain… Expand
Review
1977
Review
1977
Is there a brain renin-angiotensin system?
  • I. Reid
  • Circulation research
  • 1977
    • Corpus ID: 8499566
SINCE THE original demonstration by Bickerton and Buckley that angiotensin II acts directly on the central nervous system to… Expand
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Highly Cited
1972
Highly Cited
1972
DISTRIBUTION AND PROPERTIES OF ANGIOTENSIN CONVERTING ENZYME OF RAT BRAIN
Abstract— Angiotensin converting enzyme of rat brain was studied using Hip‐His‐Leu as substrate. The highest specific activity of… Expand
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