bivalirudin

Known as: Phe-Pro-Arg-Pro-(Gly)4-Asn-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr-Leu, Phe-Pro-Arg-Pro-(Gly)4-desulfohirudin-(53-64), Bivalirudinum 
A 20 amino acid long synthetic peptide with thrombin-specific anticoagulant properties. Bivalirudin reversibly binds thrombin, free as well as clot… (More)

Topic mentions per year

Topic mentions per year

1989-2017
05010019892017

Papers overview

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Highly Cited
2014
Highly Cited
2014
BACKGROUND Bivalirudin, with selective use of glycoprotein (GP) IIb/IIIa inhibitor agents, is an accepted standard of care in… (More)
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Highly Cited
2013
Highly Cited
2013
BACKGROUND Bivalirudin, as compared with heparin and glycoprotein IIb/IIIa inhibitors, has been shown to reduce rates of bleeding… (More)
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Highly Cited
2011
Highly Cited
2011
BACKGROUND Primary results of the HORIZONS-AMI trial have been previously reported. In this final report, we aimed to assess 3… (More)
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Highly Cited
2009
Highly Cited
2009
BACKGROUND In the HORIZONS-AMI trial, patients with acute ST-segment elevation myocardial infarction (STEMI) undergoing… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND Treatment with the direct thrombin inhibitor bivalirudin, as compared with heparin plus glycoprotein IIb/IIIa… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND Whether bivalirudin is superior to unfractionated heparin in patients with stable or unstable angina who undergo… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND The aim of this study was to assess anticoagulation with the direct thrombin inhibitor bivalirudin during percutaneous… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND Current guidelines for patients with moderate- or high-risk acute coronary syndromes recommend an early invasive… (More)
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Highly Cited
2003
Highly Cited
2003
CONTEXT The direct thrombin inhibitor bivalirudin has been associated with better efficacy and less bleeding than heparin during… (More)
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Highly Cited
1995
Highly Cited
1995
BACKGROUND Heparin is often administered during and after coronary angioplasty to prevent closure of the dilated vessel. However… (More)
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