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bivalirudin

Known as: Phe-Pro-Arg-Pro-(Gly)4-Asn-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr-Leu, Phe-Pro-Arg-Pro-(Gly)4-desulfohirudin-(53-64), Bivalirudinum 
A 20 amino acid long synthetic peptide with thrombin-specific anticoagulant properties. Bivalirudin reversibly binds thrombin, free as well as clot… 
National Institutes of Health

Related topics

Related topics

13 relations
Angina, UnstableDrug AllergyHemorrhagic DisordersMyocardial Ischemia

Narrower (4)

AngiomaxBG 8967HirulogHirulog-1

Broader (4)

AntithrombinsHirudinsPeptide FragmentsRecombinant Proteins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2010
Review
2010
Agents for the treatment of heparin-induced thrombocytopenia.
Highly Cited
2006
Highly Cited
2006
Evaluation of Bivalirudin Treatment for Heparin‐Induced Thrombocytopenia in Critically Ill Patients with Hepatic and/or Renal Dysfunction
Study Objective. To evaluate the safety, effectiveness, and dosing of bivalirudin for treatment of heparin‐induced… 
Review
2001
Review
2001
Pharmacologic preservation of the hemostatic system during cardiac surgery.
Highly Cited
1995
Highly Cited
1995
Identification of a Discrete Region of the G Protein γ Subunit Conferring Selectivity in βγ Complex Formation (*)
The identification of multiple G protein β and γ subunit subtypes suggests a potential diversity of βγ heterodimers, which may… 
Highly Cited
1990
Highly Cited
1990
Cardioactive neuropeptide Phe-Met-Arg-Phe-NH2 (FMRFamide) and novel related peptides are encoded in multiple copies by a single gene in the snail Lymnaea stagnalis
The neuropeptide Phe-Met-Arg-Phe-NH2 (FMRFamide) is a potent cardioactive neuropeptide in Lymnaea stagnalis. Isolation and… 
Highly Cited
1983
Highly Cited
1983
Mammalian tissue trypsin-like enzymes. Comparative reactivities of human skin tryptase, human lung tryptase, and bovine trypsin with peptide 4-nitroanilide and thioester substrates.
Highly Cited
1982
Highly Cited
1982
The primary translation product of rat intestinal apolipoprotein A-I mRNA is an unusual preproprotein.
Highly Cited
1980
Highly Cited
1980
Tubulinyl‐tyrosine Carboxypeptidase from Chicken Brain: Properties and Partial Purification
Abstract: Tyrosine can be released from tubulinyl‐tyrosine by the action of a brain carboxypeptidase. The molecular weight of… 
Highly Cited
1978
Highly Cited
1978
The complete amino-acid sequence of histone H2B(3) from sperm of the sea urchin Parechinus angulosus.
The primary structure of a third H2B histone isolated from sperm of the sea urchin Parechinus angulosus has been determined. H2B… 
Highly Cited
1977
Highly Cited
1977
The complete amino-acid sequence of histone H2B(2) from sperm of the sea urchin Parechinus angulosus.
Sperm histone H2B(2)Parechinus consists of a single polypeptide chain of the following 143 amino acids: Pro-Arg-Ser-Pro-Ala-Lys… 
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