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bisantrene

Known as: 9,10-Anthracenedicarboxaldehyde, bis((4,5-dihydro-1H-imidazol-2-yl)hydrazone), 9,10-Anthracenedicarboxaldehyde Bis(2-imidazolin-2-yl)hydrazone, 9,10,Anthracenedicarboxaldehyde 
An anthracenyl bishydrazone with antineoplastic activity. Bisantrene intercalates with and disrupts the configuration of DNA, resulting in DNA single… 
National Institutes of Health

Related topics

Related topics

7 relations

Broader (2)

AnthracenesAntibiotics, Antineoplastic

Narrower (4)

CL 216942NSC 337766Zantrenebisantrene dihydrochloride
NCIt Antineoplastic Agent Terminology

Papers overview

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Highly Cited
2008
Highly Cited
2008
Transcriptome sequencing of malignant pleural mesothelioma tumors
Cancers arise by the gradual accumulation of mutations in multiple genes. We now use shotgun pyrosequencing to characterize RNA… 
Highly Cited
2006
Highly Cited
2006
Bile acids in combination with low pH induce oxidative stress and oxidative DNA damage: relevance to the pathogenesis of Barrett’s oesophagus
Background: Barrett’s oesophagus is a premalignant condition associated with an increased risk for the development of oesophageal… 
Highly Cited
2005
Highly Cited
2005
An autosomal dominant cerebellar ataxia linked to chromosome 16q22.1 is associated with a single-nucleotide substitution in the 5' untranslated region of the gene encoding a protein with spectrin…
Autosomal dominant cerebellar ataxia (ADCA) is a group of heterogeneous neurodegenerative disorders. By positional cloning, we… 
Review
2002
Review
2002
Spinocerebellar ataxias in the Netherlands: Prevalence and age at onset variance analysis
BackgroundInternational prevalence estimates of autosomal dominant cerebellar ataxias (ADCA) vary from 0.3 to 2.0 per 100,000… 
Highly Cited
2001
Highly Cited
2001
Histologic and immunophenotypic classification of cervical carcinomas by expression of the p53 homologue p63: a study of 250 cases.
Recent studies of the p53 homologue p63 indicate that this gene is preferentially expressed in basal and immature cervical… 
Highly Cited
1999
Highly Cited
1999
Autosomal dominant cerebellar ataxia type I: oculomotor abnormalities in families with SCA1, SCA2, and SCA3
Abstract Forty-six patients suffering from autosomal dominant cerebellar ataxia type I (ADCA I) underwent to a genotype-phenotype… 
Highly Cited
1999
Highly Cited
1999
Molecular and clinical study of 18 families with ADCA type II: evidence for genetic heterogeneity and de novo mutation.
The SCA7 mutation has been found in 54 patients and 7 at-risk subjects from 17 families who have autosomal dominant cerebellar… 
Highly Cited
1997
Highly Cited
1997
Competence and virulence of Streptococcus pneumoniae: Adc and PsaA mutants exhibit a requirement for Zn and Mn resulting from inactivation of putative ABC metal permeases
The adcCBA putative operon of Streptococcus pneumoniae, an important human pathogen, was identified in a search for… 
Highly Cited
1997
Highly Cited
1997
The prevalence and wide clinical spectrum of the spinocerebellar ataxia type 2 trinucleotide repeat in patients with autosomal dominant cerebellar ataxia.
The dominant cerebellar ataxias (ADCAs) represent a clinically and genetically heterogeneous group of disorders linked by… 
Highly Cited
1985
Highly Cited
1985
Application of a human tumor colony-forming assay to new drug screening.
The applicability of a human tumor colony-forming assay to drug screening was investigated in terms of feasibility, validity, and… 
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