Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

beta-Lactamase

Known as: Beta lactamase, beta-Lactamases [Chemical/Ingredient], Beta lactamases 
Enzymes found in many bacteria which catalyze the hydrolysis of the amide bond in the beta-lactam ring. Well known antibiotics destroyed by these… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
OBJECTIVES To develop a rapid and reliable tool to detect by multiplex PCR assays the most frequently widespread beta-lactamase… Expand
Is this relevant?
Review
2008
Review
2008
Extended-spectrum beta-lactamases (ESBLs) represent a major threat among resistant bacterial isolates. The first types described… Expand
  • table 1
  • figure 1
Is this relevant?
Review
2005
Review
2005
Enterobacteriaceae, especially Klebsiella spp. producing extended-spectrum beta-lactamases (ESBLs) such as SHV and TEM types… Expand
  • figure 1
Is this relevant?
Review
2001
Review
2001
  • P. Bradford
  • Clinical Microbiology Reviews
  • 2001
  • Corpus ID: 37436482
SUMMARY β-Lactamases continue to be the leading cause of resistance to β-lactam antibiotics among gram-negative bacteria. In… Expand
Is this relevant?
Highly Cited
2001
Highly Cited
2001
The prevalence of antibiotic resistance among extended-spectrum beta-lactamase (ESBL)--producing Escherichia coli and Klebsiella… Expand
Is this relevant?
Highly Cited
1998
Highly Cited
1998
Gene expression was visualized in single living mammalian cells with beta-lactamase as a reporter that hydrolyzes a substrate… Expand
Is this relevant?
Review
1998
Review
1998
SUMMARY Bacteria belonging to the genus Klebsiella frequently cause human nosocomial infections. In particular, the medically… Expand
  • table 1
  • table 2
  • table 3
  • figure 1
  • figure 2
Is this relevant?
Review
1995
Review
1995
A classification scheme for b-lactamases based on functional characteristics is presented. Three major groups of enzymes are… Expand
  • table 1
  • table 2
  • table 4
  • table 5
  • table 7
Is this relevant?
Highly Cited
1988
Highly Cited
1988
Before 1985 at the Pitié-Salpêtrière Hospital in Paris (2,400 beds), resistance to cefotaxime in clinical isolates of… Expand
Is this relevant?
Highly Cited
1980
Highly Cited
1980
  • R. Ambler
  • Philosophical transactions of the Royal Society…
  • 1980
  • Corpus ID: 32518904
The beta-lactamases are widely distributed in both Gram-positive and Gram-negative bacteria. They all inactivate penicillins and… Expand
Is this relevant?