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American Journal of Physiology: Gastrointestinal and Liver Physiology American Journal of Physiology: Heart and Circulatory Physi- QlQgY American Journal of Physiology: Regulatory, Integrative and…
s Invited for Fourth Annual Workshop on PULMONARY PHYSIOLOGY AND FUNCTlON TESTlNG IN SMALL LABORATORY ANI Satellite Conference to the Annual Meeting of the AMERICAN THORACIC SOCIETY
Gastrin-releasing peptide and cancer.
Over the past 20 years, abundant evidence has been collected to suggest that gastrin-releasing peptide (GRP) and its receptors play an important role in the development of a variety of cancers. In… Expand
Divalent metal ions at the active sites of the EcoRV and EcoRI restriction endonucleases.
Restriction enzymes cannot cleave DNA without a metal ion cofactor. The specificities of the EcoRV and EcoRI endonucleases for metals were studied by measuring DNA cleavage rates with several metal… Expand
P21-activated kinase 1 stimulates colon cancer cell growth and migration/invasion via ERK- and AKT-dependent pathways.
The p21-activated kinase (PAK) family of serine/threonine kinases plays an important role in cell proliferation, survival and motility, as well as in cell transformation and tumor progression. PAK1… Expand
Specific Enzymic Methylation of an Arginine in the Experimental Allergic Encephalomyelitis Protein from Human Myelin
A cytoplasmic enzyme from guinea pig brain was shown to transfer methyl groups from S-adenosylmethionine to only one of 19 arginine residues in the basic protein from human brain. The products were… Expand
BRIEF REVIEW BIOLOGY OF GUT CHOLECYSTOKININ AND GASTRIN RECEPTORS
1. The stomach hormone gastrin and the intestinal hormone cholecystokinin (CCK) share a common C‐terminal pentapep‐tide sequence but have different biological roles. Gastrin is the major stimulant of… Expand
HGF regulates tight junctions in new nontumorigenic gastric epithelial cell line.
- F. Hollande, E. Blanc, +4 authors A. Choquet
- Biology, Medicine
- American journal of physiology. Gastrointestinal…
- 1 May 2001
The regulation of intercellular adhesion by hepatocyte growth factor (HGF) was examined on a novel nontumorigenic gastric epithelial cell line (IMGE-5) derived from H-2Kb-tsA58 transgenic mice.… Expand
PAK1 interacts with beta-catenin and is required for the regulation of the beta-catenin signalling pathway by gastrins.
Beta-catenin regulates cell-cell adhesion by binding to E-cadherin at the cell membrane and, when translocated into the nucleus, mediates signalling by activation of transcription factors such as… Expand
Binding of Gastrin17 to Human Gastric Carcinoma Cell Lines
The hormone gastrin stimulates acid secretion by gastric parietal cells and acts as a growth factor for the gastric mucosa. Gastrin receptors with dissociation constants of approximately 0.5 nm have… Expand
The Role of Hypoxia-Inducible Factor 1α in Determining the Properties of Castrate-Resistant Prostate Cancers
Background Castrate-resistant prostate cancer (CRPC) is a lethal condition in patients receiving androgen deprivation therapy for prostate cancer (PC). Despite numerous studies showing the expression… Expand