• Publications
  • Influence
American Journal of Physiology: Gastrointestinal and Liver Physiology American Journal of Physiology: Heart and Circulatory Physi- QlQgY American Journal of Physiology: Regulatory, Integrative and
s Invited for Fourth Annual Workshop on PULMONARY PHYSIOLOGY AND FUNCTlON TESTlNG IN SMALL LABORATORY ANI Satellite Conference to the Annual Meeting of the AMERICAN THORACIC SOCIETY
  • 124
  • 11
Gastrin-releasing peptide and cancer.
Over the past 20 years, abundant evidence has been collected to suggest that gastrin-releasing peptide (GRP) and its receptors play an important role in the development of a variety of cancers. InExpand
  • 154
  • 9
Divalent metal ions at the active sites of the EcoRV and EcoRI restriction endonucleases.
Restriction enzymes cannot cleave DNA without a metal ion cofactor. The specificities of the EcoRV and EcoRI endonucleases for metals were studied by measuring DNA cleavage rates with several metalExpand
  • 123
  • 5
P21-activated kinase 1 stimulates colon cancer cell growth and migration/invasion via ERK- and AKT-dependent pathways.
The p21-activated kinase (PAK) family of serine/threonine kinases plays an important role in cell proliferation, survival and motility, as well as in cell transformation and tumor progression. PAK1Expand
  • 86
  • 5
Specific Enzymic Methylation of an Arginine in the Experimental Allergic Encephalomyelitis Protein from Human Myelin
A cytoplasmic enzyme from guinea pig brain was shown to transfer methyl groups from S-adenosylmethionine to only one of 19 arginine residues in the basic protein from human brain. The products wereExpand
  • 103
  • 4
1. The stomach hormone gastrin and the intestinal hormone cholecystokinin (CCK) share a common C‐terminal pentapep‐tide sequence but have different biological roles. Gastrin is the major stimulant ofExpand
  • 60
  • 4
HGF regulates tight junctions in new nontumorigenic gastric epithelial cell line.
The regulation of intercellular adhesion by hepatocyte growth factor (HGF) was examined on a novel nontumorigenic gastric epithelial cell line (IMGE-5) derived from H-2Kb-tsA58 transgenic mice.Expand
  • 72
  • 3
PAK1 interacts with beta-catenin and is required for the regulation of the beta-catenin signalling pathway by gastrins.
Beta-catenin regulates cell-cell adhesion by binding to E-cadherin at the cell membrane and, when translocated into the nucleus, mediates signalling by activation of transcription factors such asExpand
  • 58
  • 3
Binding of Gastrin17 to Human Gastric Carcinoma Cell Lines
The hormone gastrin stimulates acid secretion by gastric parietal cells and acts as a growth factor for the gastric mucosa. Gastrin receptors with dissociation constants of approximately 0.5 nm haveExpand
  • 45
  • 3
The Role of Hypoxia-Inducible Factor 1α in Determining the Properties of Castrate-Resistant Prostate Cancers
Background Castrate-resistant prostate cancer (CRPC) is a lethal condition in patients receiving androgen deprivation therapy for prostate cancer (PC). Despite numerous studies showing the expressionExpand
  • 59
  • 3