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bestrabucil

Known as: Atrimustine, Estra-1,3,5(10)-triene-3,17-diol (17beta)-, 3-benzoate 17-((4-(4-(bis(2-chloroethyl)amino)phenyl)-1-oxobutoxy)acetate), Estradiol 3-benzoate 17-glycolate, 4-(p-(bis(2-chloroethyl)amino)phenyl)butyrate 
The benzoate of a estradiol-chlorambucil conjugate. (NCI)
National Institutes of Health

Related topics

Related topics

6 relations

Broader (4)

Antineoplastic AgentsChlorambucilEstradiolImmunosuppressive Agents

Narrower (1)

KM 2210
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1997
1997
[Acute myelogenous leukemia (M4) occurring during chronic lymphocytic leukemia].
A 68 year-old-man was first found to have CLL with IgG, kappa monoclonal gammopathy 6 years ago. Bestrabucil (total dose 35,150… 
1995
1995
Growth inhibitory effect of estrogen conjugated drugs against primary cultured breast cancer cells.
An in vitro assay method for predicting the hormonal response of primary cultured cells was used in 38 women with breast… 
1994
1994
INHIBITORY EFFECTS OF BESTRABUCIL, A CONJUGATE OF CHLORAMBUCIL AND ESTRADIOL, ON THE PRODUCTION OF ANDROGEN‐INDUCED GROWTH FACTOR(S) BY SHIONOGI CARCINOMA 115 CELLS
It is known that diffusible trophic factors play an important role in both the normal and cancerous growth regulatory processes… 
1992
1992
Adult T‐cell leukemia developing during immunosuppressive treatment in a renal transplant recipient
We report a case of a 32‐year‐old male, an asymptomatic carrier of human T‐cell leukemia virus type 1 (HTLV‐1), who underwent a… 
1991
1991
A combination trial of human lymphoblastoid interferon and bestrabucil (KM2210) for adult T‐cell leukemia–lymphoma
Both human lymphoblastoid interferon (HLBI) and bestrabucil, the conjugate of chlorambucil and β‐estradiol, have antitumor… 
1986
1986
Antitumor Activity and Pharmacokinetics of Estra-1,3,5 (10)-Triene-3,17β-Diol, 3-Benzoate, 17-((4-(4-(Bis (2-Chioroethyl)Amino)Phenyl)-1-Oxobutoxy) Acetate) (Bestrabucil) in Human Tumor Xenografts…
: Bestrabucil (KM2210), the benzoate of an estradiol-chlorambucil conjugate, was used experimental cancer chemotherapy against 13… 
1986
1986
[Early phase II trial of bestrabucil in hematological malignancies].
Thirty-three patients with various hematological malignancies were treated with Bestrabucil, the benzoate of an estradiol… 
1986
1986
[Phase I study of bestrabucil (KM 2210)].
A phase I study was performed on a newly developed antitumor agent, Bestrabucil (KM 2210). The study was started at an initial… 
1986
1986
[Clinical trial of bestrabucil (KM 2210) on hematopoietic malignancies].
Twenty-one patients were entered for a clinical study of KM 2210, the benzoate of an estradiol-chlorambucil conjugate, in the… 
1984
1984
[Bestrabacil: a possible target-oriented anticancer agent].
Bestrabucil, the benzoate of an estradiol-chlorambucil conjugate, was initially developed as a target-oriented anticancer agent… 
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