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bestrabucil

Known as: Atrimustine, Estra-1,3,5(10)-triene-3,17-diol (17beta)-, 3-benzoate 17-((4-(4-(bis(2-chloroethyl)amino)phenyl)-1-oxobutoxy)acetate), Estradiol 3-benzoate 17-glycolate, 4-(p-(bis(2-chloroethyl)amino)phenyl)butyrate 
The benzoate of a estradiol-chlorambucil conjugate. (NCI)
National Institutes of Health

Papers overview

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1995
1995
An in vitro assay method for predicting the hormonal response of primary cultured cells was used in 38 women with breast… Expand
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1994
1994
It is known that diffusible trophic factors play an important role in both the normal and cancerous growth regulatory processes… Expand
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1992
1992
We report a case of a 32-year-old male, an asymptomatic carrier of human T-cell leukemia virus type 1 (HTLV-1), who underwent a… Expand
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1991
1991
Both human lymphoblastoid interferon (HLBI) and bestrabucil, the conjugate of chlorambucil and beta-estradiol, have antitumor… Expand
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1986
1986
Thirty-three patients with various hematological malignancies were treated with Bestrabucil, the benzoate of an estradiol… Expand
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1986
1986
Twenty-one patients were entered for a clinical study of KM 2210, the benzoate of an estradiol-chlorambucil conjugate, in the… Expand
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1986
1986
Thirteen patients with hematological neoplasms were treated with Bestrabucil (100 mg/day po, total dose 700-9,900 mg), which is… Expand
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1986
1986
Bestrabucil, a chlorambucil-estradiol conjugate known to accumulate in malignant cells irrespective of the presence or absence of… Expand
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1984
1984
Bestrabucil, the benzoate of an estradiol-chlorambucil conjugate, was initially developed as a target-oriented anticancer agent… Expand
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