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Chlorambucil

Known as: Chlorobutin, Chloroambucil, gamma-[p-di(2-chloroethyl)aminophenyl]butyric acid 
A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic… 
National Institutes of Health

Related topics

Related topics

38 relations
Alkylating Activity [MoA]Chlorambucil 2 MG Oral Tablet [Leukeran]Chlorambucil-Prednisone Regimen (CP Regimen)Choriocarcinoma

Narrower (13)

Alti-chlorambucilAmboclorinCB-1348LOPP protocol 1

Broader (2)

Antineoplastic Agents, Alkylatinghaloalkylamine

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2003
2003
Impact of three-spined stickleback Gasterosteus aculeatus on zooplankton and chl a in shallow, eutrophic, brackish lakes
The 3-spined stickleback Gasterosteus aculeatus often dominates fish communities in eu- trophic, brackish, north-temperate lakes… 
2000
2000
Expression of NADPH-Protochlorophyllide oxidoreductase gene in fully green leaves of cucumber.
Photoreduction of protochlorophyllide a to chlorophyllide a that is catalyzed by NADPH-protochlorophyllide oxidoreductase (NPR… 
1993
1993
Resonances in the photolysis of HCl in Ar-CHl: Imaging of a resonance wave function in the photofragment angular distribution.
The photodissociation of HCl in the Ar-HCl cluster is studied theoretically, with the focus on the angular distribution of the H… 
Highly Cited
1986
Highly Cited
1986
Specific targeting of chlorambucil to tumors with the use of monoclonal antibodies.
The concept of attaching cytotoxic drugs, such as the alkylating agent chlorambucil (CBL), to "tumor-specific" antibodies for the… 
1980
1980
Comparative pharmacokinetics of chlorambucil and melphalan in man.
We have studied the pharmacokinetics of orally administered chlorambucil and melphalan in patients with hematologic malignancies… 
1979
1979
Genetic control of cobalamin binding in normal and mutant cells: assignment of the gene for 5-methyltetrahydrofolate:L-homocysteine S-methyltransferase to human chromosome 1.
When extracts prepared from cultured human or rodent fibroblasts grown in medium containing [(57)Co]cobalamin were analyzed by… 
1975
1975
Suppression of an AKR lymphoma by antibody and chlorambucil.
A cell-surface localizing xenogeneic antibody against an AKR mouse lymphoma of spontaneous origin could be bound to chlorambucil… 
Highly Cited
1973
Highly Cited
1973
Long-lasting remission of Behcet's disease after chlorambucil therapy.
Beh§et (I937) drew attention to a syndrome characterized by a triad of symptoms: iritis, aphthous ulceration of the mouth, and… 
1967
1967
Chromosome changes in embryos treated with various teratogens.
The association of chromosome changes with certain syndromes of congenital malformations has raised new questions as to the… 
1958
1958
The Influence of Chemical Structure on -oxidation by Soil Nocardias
Studies of the β-oxidation of the fatty acid side-chain of certain ω-aryl- and ω-aryloxy-n-alkylcarboxylic acids by Nocardia…