Chlorambucil

Known as: Chlorobutin, Chloroambucil, gamma-[p-di(2-chloroethyl)aminophenyl]butyric acid 
A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1936-2017
010020019362016

Papers overview

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Review
2017
Review
2017
Efficient intracellular trafficking and targeted delivery to the site of action are essential to overcome the current drawbacks… (More)
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Highly Cited
2014
Highly Cited
2014
BACKGROUND The monoclonal anti-CD20 antibody rituximab, combined with chemotherapeutic agents, has been shown to prolong overall… (More)
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Highly Cited
2009
Highly Cited
2009
Although chronic lymphocytic leukemia (CLL) is a disease of elderly patients, subjects older than 65 years are heavily… (More)
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Highly Cited
2007
Highly Cited
2007
PURPOSE We conducted a randomized trial to evaluate the efficacy and safety of intravenous alemtuzumab compared with chlorambucil… (More)
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Highly Cited
2007
Highly Cited
2007
PURPOSE Rituximab has been shown to be active in follicular lymphoma (FL), both as monotherapy and in combination with… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND Fludarabine is an effective treatment for chronic lymphocytic leukemia that does not respond to initial treatment with… (More)
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Highly Cited
1998
Highly Cited
1998
BACKGROUND To determine whether chlorambucil treatment benefits patients with indolent chronic lymphocytic leukemia (CLL), we… (More)
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Highly Cited
1998
Highly Cited
1998
To assess whether chlorambucil or cyclophosphamide may have a better therapeutic index in patients with idiopathic membranous… (More)
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Highly Cited
1994
Highly Cited
1994
When yeast cells reach a critical size, they initiate bud formation, spindle pole body duplication, and DNA replication almost… (More)
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Highly Cited
1985
Highly Cited
1985
We found inconsistencies in the commonly used data for chlorophyll analysis in 80% acetone. Recently developed extinction… (More)
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