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bergamottin

Known as: 5-geranoxypsoralen 
 
National Institutes of Health

Papers overview

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2014
2014
Persistent activation of signal transducers and activator of transcription 3 (STAT3) has been closely related to growth, survival… Expand
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Review
2005
Review
2005
Consistent with its highest abundance in humans, cytochrome P450 (CYP) 3A is responsible for the metabolism of about 60% of… Expand
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Review
2004
Review
2004
P‐glycoprotein (Pgp) is a 170 kDa phosphorylated glycoprotein encoded by human MDR1 gene. It is responsible for the systemic… Expand
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Highly Cited
2003
Highly Cited
2003
Components of grapefruit juice may impair the activity of intestinal cytochrome P450 (CYP) 3A enzymes, sometimes resulting in… Expand
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Highly Cited
2003
Highly Cited
2003
Objectives: Our objective was to assess the importance of bergamottin in drug interactions through comparisons between grapefruit… Expand
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2002
2002
We investigated the effect of bergamottin, a major furanocoumarin in grapefruit juice, on phase I and phase II drug-metabolizing… Expand
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Highly Cited
2001
Highly Cited
2001
Our objective was to determine whether Seville orange juice produces a grapefruit juice–like interaction with felodipine and… Expand
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Highly Cited
2000
Highly Cited
2000
To determine whether unprocessed grapefruit can cause a drug interaction, whether the active ingredients are naturally occurring… Expand
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Highly Cited
1998
Highly Cited
1998
Grapefruit juice has been found to significantly increase oral bioavailability of several drugs metabolized by cytochrome P450… Expand
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Highly Cited
1997
Highly Cited
1997
Grapefruit juice increases the oral availability of a variety of CYP3A4 substrates. It has been shown that recurrent grapefruit… Expand
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