bergamottin

Known as: 5-geranoxypsoralen 
 
National Institutes of Health

Papers overview

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2012
2012
Grapefruit juice (GJ) is a well known Cytochrome P450 (CYP) inhibitor; CYP3A is one of the most affected subfamily leading to… (More)
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2012
2012
Previous studies have demonstrated that bergamottin (BG), a component of grapefruit juice, is a mechanism-based inactivator of… (More)
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2006
2006
Cytochromes P450 (P450) 2B6 and 3A5 are inactivated by bergamottin (BG). P450 2B6 metabolized BG primarily to M3 and M4 and one… (More)
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2005
2005
Bergamottin (BG), a component of grapefruit juice, is a mechanism-based inactivator of cytochromes P450 (P450) 2B6 and 3A5 in the… (More)
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Review
2004
Review
2004
It has been well established that the formation of reactive metabolites of drugs is associated with drug toxicity. Similarly… (More)
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2004
2004
OBJECTIVES Our objectives were to evaluate the contribution of bergamottin to the grapefruit juice-felodipine interaction and to… (More)
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Highly Cited
2003
Highly Cited
2003
OBJECTIVES Our objective was to assess the importance of bergamottin in drug interactions through comparisons between grapefruit… (More)
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2002
2002
We investigated the effect of bergamottin, a major furanocoumarin in grapefruit juice, on phase I and phase II drug-metabolizing… (More)
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Highly Cited
2000
Highly Cited
2000
OBJECTIVES To determine whether unprocessed grapefruit can cause a drug interaction, whether the active ingredients are naturally… (More)
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Highly Cited
1997
Highly Cited
1997
Grapefruit juice increases the oral availability of a variety of CYP3A4 substrates. It has been shown that recurrent grapefruit… (More)
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