Stratum Corneum Is an Effective Barrier to TiO2 and ZnO Nanoparticle Percutaneous Absorption
- P. Filipe, J.N. Silva, T. Pinheiro
- MedicineSkin Pharmacology and Physiology
- 18 August 2009
TiO2 or ZnO nanoparticles are absent or their levels are too low to be tested under the stratum corneum in human viable epidermal layers, therefore, significant penetration towards the underlying keratinocytes is unlikely.
Assessment of Laboratory and Field Assays of Sunlight-Induced Killing of Mosquito Larvae by Photosensitizers
- B. Dondji, S. Duchon, J. Schrével
- ChemistryJournal of medical entomology
- 1 July 2005
Abstract The effectiveness of light-induced killing of mosquito larvae in the presence of photosensitizers was studied with larvae of Aedes aegypti (L.), Anopheles stephensi (Liston), and Culex…
Endoplasmic reticulum and Golgi apparatus are the preferential sites of Foscan® localisation in cultured tumour cells
- M. Teiten, L. Bezdetnaya, P. Morlière, R. Santus, F. Guillemin
- BiologyBritish Journal of Cancer
- 13 January 2003
This is the first study to demonstrate unambiguously that the endoplasmic reticulum and Golgi apparatus are preferential sites of Foscan® accumulation in the MCF-7 cell line.
Ultraviolet‐A induces activation of AP‐1 in cultured human keratinocytes
- M. Djavaheri-Mergny, J. Mergny, J. Mazière
- Biology, MedicineFEBS Letters
- 8 April 1996
UVA radiation stimulates ceramide production: relationship to oxidative stress and potential role in ERK, JNK, and p38 activation.
- C. Maziére, M. Conte, J. Mazière
- BiologyBiochemical and Biophysical Research…
- 23 February 2001
The results provide a possible mechanism for UVA-induced activation of stress kinases via ceramide formation, and show that, downstream of CER, UVA activated the Ser/Thr kinases ERK, JNK, and p38.
Oxygen dependency of tumor cell killing in vitro by light-activated Photofrin II.
- J. Chapman, C. Stobbe, M. Arnfield, R. Santus, J. Lee, M. McPhee
- Biology, MedicineRadiation Research
- 1 April 1991
Asynchronous populations of mouse EMT-6 tumor cells were treated with Photofrin II and exposed to various doses of 630 nm light in slowly stirred suspensions which had been equilibrated with various…
Anti- and pro-oxidant effects of quercetin in copper-induced low density lipoprotein oxidation. Quercetin as an effective antioxidant against pro-oxidant effects of urate.
- P. Filipe, J. Haigle, P. Morlière
- BiologyEuropean Journal of Biochemistry
- 1 May 2004
It is demonstrated that quercetin alone behaves as a pro-oxidant towards preoxidized LDL, and it is shown that the pro- oxidant activity of urate can be inhibited by quercets, as already observed with other antioxidants.
The role of the low density lipoprotein receptor pathway in the delivery of lipophilic photosensitizers in the photodynamic therapy of tumours.
- J. Mazière, P. Morlière, R. Santus
- Biology, MedicineJournal of Photochemistry and Photobiology. B…
- 1 March 1991
Tolyporphin: a natural product from cyanobacteria with potent photosensitizing activity against tumor cells in vitro and in vivo.
- P. Morlière, J. Mazière, J. Chapman
- Biology, ChemistryCancer Research
- 15 August 1998
The outstanding PDT activity of TP observed in vivo may be due to its unique biodistribution properties, in particular much less extraction by the liver, resulting in a higher delivery to other tissues, including tumor.
Damage to mitochondria of cultured human skin fibroblasts photosensitized by fluoroquinolones.
- G. Ouédraogo, P. Morlière, R. Santus, Miranda, J. Castell
- Biology, ChemistryJournal of Photochemistry and Photobiology. B…
- 1 October 2000
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