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azaspirene

 
National Institutes of Health

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2018
2018
Azaspirene and related congeners, which possess various biological activities, have a unique spirocyclic core structure. However… Expand
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2017
2017
The total synthesis of (±)-azaspirene (1) was achieved in a total of six steps from commercially available materials. Keys to the… Expand
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2016
2016
Author(s): Banasik, Brent | Advisor(s): Bergdahl, Mikael; Molinski, Tadeusz | Abstract: Lagunamide A represents a class of novel… Expand
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2015
2015
Uterine carcinosarcoma is a highly aggressive gynecological neoplasm that responds poorly to conventional chemotherapy and… Expand
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2014
2014
Author(s): Schmit, David John | Abstract: Chemical studies toward the synthesis of an angiogenesis inhibitor azaspirene is… Expand
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2014
2014
Pseurotins comprise a family of structurally related Aspergillal natural products having interesting bioactivity. However, little… Expand
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2009
2009
 
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2008
2008
Angiogenesis is an inevitable event in tumor progression and metastasis, and thus has been a compelling target for cancer therapy… Expand
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2007
2007
Hydrozirconation of alkynes, utilizing Schwartz's reagent, }Cp2Zr(H)Cl}, is a superb protocol for making regioselective… Expand
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2002
2002
[structure: see text] Azaspirene isolated from the fungus Neosartorya sp. is a novel angiogenesis inhibitor with a 1-oxa-7… Expand
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