avibactam

 
National Institutes of Health

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Review
2016
Review
2016
During the last decade infections caused by MDR Gram-negative bacteria (GNB) have become increasingly prevalent. Because of their… (More)
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Review
2015
Review
2015
The management of infections due to Klebsiella pneumoniae has been complicated by the emergence of antimicrobial resistance… (More)
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2015
2015
β-Lactamase enzymes (EC 3.5.2.6) are a significant threat to the continued use of β-lactam antibiotics to treat infections. A… (More)
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2014
2014
Avibactam is a novel non-β-lactam β-lactamase inhibitor that inhibits a wide range of β-lactamases. These include class A, class… (More)
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Review
2014
Review
2014
The emergence of one of the most recently described carbapenemases, namely, the New Delhi metallo-lactamase (NDM-1), constitutes… (More)
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2014
2014
OBJECTIVES Two β-lactams, cefoxitin and imipenem, are part of the reference treatment for pulmonary infections with Mycobacterium… (More)
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Highly Cited
2013
Highly Cited
2013
OBJECTIVES Avibactam, a novel non-β-lactam β-lactamase inhibitor, restores the in vitro activity of ceftazidime against class A… (More)
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2013
2013
This study was conducted to determine the safety, tolerability, and pharmacokinetics of intravenous doses of ceftaroline fosamil… (More)
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Highly Cited
2012
Highly Cited
2012
Avibactam is a β-lactamase inhibitor that is in clinical development, combined with β-lactam partners, for the treatment of… (More)
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2012
2012
The objective of this study was to investigate the in vitro antibacterial activity of avibactam (formerly NXL104) in combination… (More)
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