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beta Lactamase Inhibitors [MoA]

Known as: beta Lactamase Inhibitors, beta-Lactamase Inhibitors 
 
National Institutes of Health

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7 relations
ClavulanateSulbactamSulbactam Sodiumavibactam
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Papers overview

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Review
2010
Review
2010
Inhibitor-based methods for the detection of KPC carbapenemase-producing Enterobacteriaceae in clinical practice by using boronic acid compounds.
Enterobacteriaceae clinical strains that produce the class A carbapenem-hydrolysing enzyme KPC (Klebsiella pneumoniae… Expand
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2006
2006
Synthesis and evaluation of ketophosph(on)ates as beta-lactamase inhibitors.
A series of amidoketophosph(on)ates of general structure PhCH2OCONHCH(R)COCHR'(CH2)n(O)P(O2-)(O)R'' (R = H, CH3; R' = H, CH3; n… Expand
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2001
2001
Design, synthesis, and evaluation of alpha-ketoheterocycles as class C beta-lactamase inhibitors.
A series of specific alpha-ketoheterocycles (benzoxazole, thiazole, imidazole, tetrazole, and thiazole-4-carboxylate) has been… Expand
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1999
1999
The synthesis and evaluation of 6-alkylidene-2'beta-substituted penam sulfones as beta-lactamase inhibitors.
Penicillin sulfones, which structurally incorporate both a 6-position alkylidene substituent and a 2'beta substituent, have been… Expand
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1998
1998
Structure-based design of beta-lactamase inhibitors. 2. Synthesis and evaluation of bridged sulfactams and oxamazins.
A series of bridged monocyclic beta-lactams activated by various groups on the beta-lactam nitrogen (X = OCH2CO2H, OSO3H) has… Expand
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1993
1993
(6R)-6-(substituted methyl)penicillanic acid sulfones: new potent beta-lactamase inhibitors.
A series of (6R)-6-(substituted methyl)penicillanic acid sulfones has been prepared starting from the corresponding 6… Expand
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1989
1989
Diketene analogs as beta-lactamase inhibitor.
Compounds having a structural analogy with diketene have been synthesized and their potencies as beta-lactamase inhibitors have… Expand
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1987
1987
Structure-activity relationships of 6-(heterocyclyl)-methylene penam sulfones; a new class of beta-lactamase inhibitors.
6-(Heterocyclyl)methylene penam sulfones (1) are effective beta-lactamase inhibitors and potent ampicillin and cefazolin… Expand
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1980
1980
[beta-lactamase inhibitors].
 
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Review
1980
Review
1980
[beta-lactamase inhibitors].
 
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