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beta Lactamase Inhibitors [MoA]

Known as: beta Lactamase Inhibitors, beta-Lactamase Inhibitors 
National Institutes of Health

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7 relations
ClavulanateSulbactamSulbactam Sodiumavibactam

Papers overview

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2006
2006
Synthesis and evaluation of ketophosph(on)ates as beta-lactamase inhibitors.
A series of amidoketophosph(on)ates of general structure PhCH2OCONHCH(R)COCHR'(CH2)n(O)P(O2-)(O)R'' (R = H, CH3; R' = H, CH3; n… 
2002
2002
Cephalosporin-derived inhibitors of beta-lactamase. Part 4: The C3 substituent.
New C3-substituted beta-lactamase inhibitors were prepared and evaluated against representative class A and class C enzymes. It… 
2001
2001
Design, synthesis, and evaluation of alpha-ketoheterocycles as class C beta-lactamase inhibitors.
A series of specific alpha-ketoheterocycles (benzoxazole, thiazole, imidazole, tetrazole, and thiazole-4-carboxylate) has been… 
2000
2000
The synthesis and evaluation of 3-substituted-7-(alkylidene)cephalosporin sulfones as beta-lactamase inhibitors.
A series of 3-substituted-7-(alkylidene)cephaloporin sulfones were prepared and evaluated as inhibitors of representative class A… 
1996
1996
Effect of beta-lactamase inhibitors on normal immune capabilities and their interactions with staphylococcal pathogenicity.
The effects of the beta-lactamase inhibitors, clavulanic acid, sulbactam and tazobactam on normal immune responses were… 
1993
1993
(6R)-6-(substituted methyl)penicillanic acid sulfones: new potent beta-lactamase inhibitors.
A series of (6R)-6-(substituted methyl)penicillanic acid sulfones has been prepared starting from the corresponding 6… 
1993
1993
Kinetics and mechanism of beta-lactamase inhibition by phosphonamidates: the quest for a proton.
Four phosphonamidates were synthesized as potential beta-lactamase inhibitors. Three were methanephosphonamidates [CH3PO2-NHR/Ar… 
1989
1989
Diketene analogs as beta-lactamase inhibitor.
Compounds having a structural analogy with diketene have been synthesized and their potencies as beta-lactamase inhibitors have… 
1987
1987
Structure-activity relationships of 6-(heterocyclyl)-methylene penam sulfones; a new class of beta-lactamase inhibitors.
6-(Heterocyclyl)methylene penam sulfones (1) are effective beta-lactamase inhibitors and potent ampicillin and cefazolin… 
Review
1980
Review
1980
[beta-lactamase inhibitors].
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