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Sulbactam

Known as: (2S,5R)-3,3-Dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid 4,4-dioxide, Sulbactam [Chemical/Ingredient], (2S,5R)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide 
A semi-synthetic beta-lactamase inhibitor. The beta-lactam ring of sulbactam irreversibly binds to beta-lactamase at or near its active site, thereby… 
National Institutes of Health

Related topics

Related topics

33 relations

Narrower (10)

6-beta-(trifluoromethanesulfonyl)amido-penicillanic acid sulfone6-diazopenicillanate sulfoneCP-45899Combactam
Amoxicillin / SulbactamAmpicillin / SulbactamAmpicillin 100 MG/ML / Sulbactam 50 MG/ML Injectable Solution [Unasyn]Ampicillin 1000 MG / Sulbactam 500 MG Injection [Unasyn]

Broader (2)

Anti-Bacterial Agentsbeta-Lactamase Inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Antimicrobial resistance in food and clinical Aeromonas isolates.
Highly Cited
2005
Highly Cited
2005
Mortality risk factors of Acinetobacter baumannii bacteraemia
Abstract 
Highly Cited
2004
Highly Cited
2004
S-oxygenation of the thioether organophosphate insecticides phorate and disulfoton by human lung flavin-containing monooxygenase 2.
Highly Cited
2002
Highly Cited
2002
Spectrum and antibiotic resistance of uropathogens from hospitalized patients with urinary tract infections: 1994-2000.
Highly Cited
2000
Highly Cited
2000
Bacteremia due to Staphylococcus aureus with reduced susceptibility to vancomycin.
Highly Cited
1999
Highly Cited
1999
Natural antibiotic susceptibility of Escherichia coli, Shigella, E. vulneris, and E. hermannii strains.
Highly Cited
1993
Highly Cited
1993
Evidence for the presence of a septide-sensitive tachykinin receptor in the circular muscle of the guinea-pig ileum.
Highly Cited
1987
Highly Cited
1987
A quantitative structure-activity relationship analysis of some 4-aminodiphenyl sulfone antibacterial agents using linear free energy and molecular modeling methods.
A set of 36 congeneric 4-aminodiphenyl sulfones with measured inhibition potencies of dihydropteroate synthase were studied by… 
Highly Cited
1986
Highly Cited
1986
Comparative activities of the beta-lactamase inhibitors YTR 830, clavulanate, and sulbactam combined with ampicillin and broad-spectrum penicillins against defined beta-lactamase-producing aerobic…
The in vitro synergistic activities of the beta-lactamase inhibitors YTR 830, clavulanate, and sulbactam, combined with… 
Highly Cited
1984
Highly Cited
1984
Characterization of the relaxant effects of vasoactive intestinal peptide (VIP) and PHI on isolated brain arteries
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