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Sulbactam

Known as: (2S,5R)-3,3-Dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid 4,4-dioxide, Sulbactam [Chemical/Ingredient], (2S,5R)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide 
A semi-synthetic beta-lactamase inhibitor. The beta-lactam ring of sulbactam irreversibly binds to beta-lactamase at or near its active site, thereby… 
National Institutes of Health

Related topics

Related topics

33 relations

Narrower (10)

6-beta-(trifluoromethanesulfonyl)amido-penicillanic acid sulfone6-diazopenicillanate sulfoneCP-45899Combactam
Amoxicillin / SulbactamAmpicillin / SulbactamAmpicillin 100 MG/ML / Sulbactam 50 MG/ML Injectable Solution [Unasyn]Ampicillin 1000 MG / Sulbactam 500 MG Injection [Unasyn]

Broader (2)

Anti-Bacterial Agentsbeta-Lactamase Inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2018
Highly Cited
2018
Thyroid Disruption by Bisphenol S Analogues via Thyroid Hormone Receptor β: in Vitro, in Vivo, and Molecular Dynamics Simulation Study.
Bisphenol S (4-hydroxyphenyl sulfone, BPS) is increasingly used as a bisphenol A (BPA) alternative. The global usage of BPS and… 
Highly Cited
2014
Highly Cited
2014
β-Lactamase inhibition by avibactam in Mycobacterium abscessus.
OBJECTIVES Two β-lactams, cefoxitin and imipenem, are part of the reference treatment for pulmonary infections with Mycobacterium… 
Review
2013
Review
2013
Clinical practice. Infective endocarditis.
Highly Cited
2009
Highly Cited
2009
High-throughput membrane surface modification to control NOM fouling.
A novel method for synthesis and screening of fouling-resistant membrane surfaces was developed by combining a high-throughput… 
Highly Cited
2008
Highly Cited
2008
Ultrafiltration of polysaccharide–protein mixtures: Elucidation of fouling mechanisms and fouling control by membrane surface modification
Highly Cited
2005
Highly Cited
2005
Synthesis of Nanoscale Bimetallic Particles in Polyelectrolyte Membrane Matrix for Reductive Transformation of Halogenated Organic Compounds
Nanosized Fe/Ni and Fe/Pd particles were synthesized in the polyacrylic acid (PAA)/polyether sulfone (PES) composite membrane… 
Highly Cited
2003
Highly Cited
2003
Hybrid epoxy‐based thermosets based on polyhedral oligosilsesquioxane: Cure behavior and toughening mechanisms
Polyhedral oligosilsesquioxane (POSS)-reinforced thermosets based on oc- taglycidyl epoxy polyhedral oligosilsesquioxane cured… 
Highly Cited
2002
Highly Cited
2002
Plasmid-Determined AmpC-Type β-Lactamases
The predominant mechanism for resistance to β-lactam antibiotics in gram-negative bacteria is the synthesis of β-lactamase. To… 
Highly Cited
2001
Highly Cited
2001
Interactions of colistin and rifampin on multidrug-resistant Acinetobacter baumannii.
Highly Cited
1991
Highly Cited
1991
In vivo evidence for tachykininergic transmission using a new NK-2 receptor-selective antagonist, MEN 10,376.
We have studied the effects of two newly developed tachykinin antagonists, MEN 10,207 and MEN 10,376, which are highly selective… 
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