Sulbactam

Known as: (2S,5R)-3,3-Dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid 4,4-dioxide, Sulbactam [Chemical/Ingredient], (2S,5R)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide 
A semi-synthetic beta-lactamase inhibitor. The beta-lactam ring of sulbactam irreversibly binds to beta-lactamase at or near its active site, thereby… (More)
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
INTRODUCTION… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Hospitals are advised to measure antibiotic use and monitor its relationship to resistance. The World Health… (More)
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Review
2006
Review
2006
The increasing trend of carbapenem resistance in Acinetobacter baumannii worldwide is a concern since it limits drastically the… (More)
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Highly Cited
2004
Highly Cited
2004
Foot infections in diabetic patients are predominantly caused by gram-positive cocci, many of which are now antibiotic resistant… (More)
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Highly Cited
2003
Highly Cited
2003
Forty consecutive patients with nosomial infections caused by multidrug-resistant Acinetobacter baumannii were treated with… (More)
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Highly Cited
2003
Highly Cited
2003
The emergence of multidrug-resistant (MDR) Acinetobacter baumannii poses a therapeutic problem. The aim of this study was to… (More)
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Highly Cited
2001
Highly Cited
2001
OBJECTIVE To assess the value of single-dose, intravenous, prophylactic ampicillin and sulbactam (AS) in the prevention of wound… (More)
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Highly Cited
1994
Highly Cited
1994
We evaluated the effects of nitric oxide (NO) generators and endogenous production of NO elicited by substance P (SP) in the… (More)
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Highly Cited
1988
Highly Cited
1988
Before 1985 at the Pitié-Salpêtrière Hospital in Paris (2,400 beds), resistance to cefotaxime in clinical isolates of… (More)
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1983
1983
Sulbactam, a new beta-lactamase inhibitor, has pharmacokinetic characteristics in humans similar to those of ampicillin and… (More)
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