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Sulbactam

Known as: (2S,5R)-3,3-Dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid 4,4-dioxide, Sulbactam [Chemical/Ingredient], (2S,5R)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide 
A semi-synthetic beta-lactamase inhibitor. The beta-lactam ring of sulbactam irreversibly binds to beta-lactamase at or near its active site, thereby… 
National Institutes of Health

Related topics

Related topics

33 relations

Narrower (10)

6-beta-(trifluoromethanesulfonyl)amido-penicillanic acid sulfone6-diazopenicillanate sulfoneCP-45899Combactam
Amoxicillin / SulbactamAmpicillin / SulbactamAmpicillin 100 MG/ML / Sulbactam 50 MG/ML Injectable Solution [Unasyn]Ampicillin 1000 MG / Sulbactam 500 MG Injection [Unasyn]

Broader (2)

Anti-Bacterial Agentsbeta-Lactamase Inhibitors

Papers overview

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2011
2011
In Vitro Efficacy of Cefepime Against Multi-Drug Resistant Pseudomonas aeruginosa – An Alarming Situation in our Setup
Background: Third generation cephalosporins are still most commonly used antibiotics empirically in our setup leading to… 
2010
2010
Extraction of Calcium and Strontium into Phenyltrifluoromethyl Sulfone by Using Synergistic Mixture of Hydrogen Dicarbollylcobaltate and "Classical" CMPO.
Solvent extraction of microamounts of calcium and strontium by a phenyltrifluoromethyl sulfone (FS 13) solution of hydrogen… 
2010
2010
In vitro activity of aminoglycosides, β lactam-β lactamases inhibitor combinations and tetracyclines against multi-drug resistant Acinetobacter baumannii, isolated from a tertiary care hospital.
, isolated from a tertiary care hospital. The study was carried out from January, 2009 - August, 2009, at the Department of… 
2007
2007
Bacteremia Caused by Rothia mucilaginosa in a Patient with Shwachman-Diamond Syndrome
Rothia mucilaginosa, previously known as Stomatococcus mucilaginosus, is a Gram-positive microrganism, which is a part of normal… 
1986
1986
Comparative activities of the beta-lactamase inhibitors YTR 830, clavulanate and sulbactam combined with extended-spectrum penicillins against ticarcillin-resistant Enterobacteriaceae and…
The in-vitro synergistic activity of YTR 830, a new beta-lactamase inhibitor, combined with four extended-spectrum penicillins… 
1986
1986
Biliary pharmacokinetics of sulbactam plus ampicillin in humans.
The biliary pharmacokinetics of sulbactam and ampicillin was investigated in 19 patients with normal liver function who were… 
1985
1985
The parenteral kinetics of ampicillin/sulbactam in man.
The kinetics of co-administered ampicillin plus sulbactam were examined at doses being used in clinical trials of this… 
1984
1984
Penicillanic acid sulfone: nature of irreversible inactivation of RTEM beta-lactamase from Escherichia coli.
When penicillanic acid sulfone in large molar excess is incubated with the RTEM beta-lactamase, the enzyme becomes inactivated… 
1984
1984
Ampicillin combined with sulbactam or metronidazole for single-dose chemoprophylaxis in major gynaecological surgery.
A double-blind, placebo-controlled and randomized trial involving a total of 295 patients was carried out to define the role of… 
1972
1972
Translation of satellite tobacco necrosis virus ribonucleic acid. II. Initiation of in vitro translation in procaryotic and eucaryotic systems.
This paper reports the N-terminal amino acid of the product of in vitro translation of satellite tobacco necrosis virus…