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Sulbactam

Known as: (2S,5R)-3,3-Dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid 4,4-dioxide, Sulbactam [Chemical/Ingredient], (2S,5R)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide 
A semi-synthetic beta-lactamase inhibitor. The beta-lactam ring of sulbactam irreversibly binds to beta-lactamase at or near its active site, thereby… Expand
National Institutes of Health

Papers overview

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Review
2013
Review
2013
From Service de Maladies Infectieuses et Tropicales, Centre Hospitalier Régional Universitaire, and Unité Mixte de Recherche 6249… Expand
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Review
2006
Review
2006
The increasing trend of carbapenem resistance in Acinetobacter baumannii worldwide is a concern since it limits drastically the… Expand
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Highly Cited
2004
Highly Cited
2004
Foot infections in diabetic patients are predominantly caused by gram-positive cocci, many of which are now antibiotic resistant… Expand
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Highly Cited
2003
Highly Cited
2003
Forty consecutive patients with nosomial infections caused by multidrug-resistant Acinetobacter baumannii were treated with… Expand
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Highly Cited
2002
Highly Cited
2002
The predominant mechanism for resistance to β-lactam antibiotics in gram-negative bacteria is the synthesis of β-lactamase. To… Expand
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Highly Cited
2001
Highly Cited
2001
As part of the SENTRY Antimicrobial Surveillance Program, a total of 1078 Acinetobacter species and 842 Stenotrophomonas… Expand
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Highly Cited
1997
Highly Cited
1997
(MRSA) with reduced suscept-ibility to vancomycin (MIC 8 mg/L). The strain was isolated from a surgical wound infection which was… Expand
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Highly Cited
1994
Highly Cited
1994
We evaluated the effects of nitric oxide (NO) generators and endogenous production of NO elicited by substance P (SP) in the… Expand
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Highly Cited
1991
Highly Cited
1991
We isolated an imipenem-resistant strain, GN17203, of Pseudomonas aeruginosa. The strain produced a beta-lactamase that… Expand
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Highly Cited
1988
Highly Cited
1988
Before 1985 at the Pitié-Salpêtrière Hospital in Paris (2,400 beds), resistance to cefotaxime in clinical isolates of… Expand
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