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aureothin

Known as: 2-methoxy-3,5-dimethyl-6-(tetrahydro-4-(2-methyl-3-(4-nitrophenyl)-2-propenylidene)-2-fur anyl)-4H-pyran-4-one, mycolutein 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Chromones

Narrower (1)

alloaureothin

Papers overview

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2013
2013
Construction and engineering of large biochemical pathways via DNA assembler.
DNA assembler enables rapid construction and engineering of biochemical pathways in a one-step fashion by exploitation of the in… 
2012
2012
Interchenar retrotransfer of aureothin intermediates in an iterative polyketide synthase module.
The course of the enigmatic iterative use of a polyketide synthase module was deduced from targeted domain inactivation in the… 
2012
2012
Pyran Formation by an Atypical CYP‐Mediated Four‐Electron Oxygenation–Cyclization Cascade in an Engineered Aureothin Pathway
Small changes, big effect: A new aureothin derivative, aureopyran, which features an unusual pyran backbone, was generated by… 
Highly Cited
2011
Highly Cited
2011
Structural fine-tuning of a multifunctional cytochrome P450 monooxygenase.
AurH is a unique cytochrome P450 monooxygenase catalyzing the stepwise formation of a homochiral oxygen heterocycle, a key… 
2010
2010
A concise route to α'-methoxy-γ-pyrones and verticipyrone based upon the desymmetrization of α,α'-dimethoxy-γ-pyrone.
Two steps is the rule : A concise synthesis of versatile α′‐methoxy‐γ‐pyrones (see scheme) is described that uses an innovative… 
2008
2008
Sequential asymmetric polyketide heterocyclization catalyzed by a single cytochrome P450 monooxygenase (AurH).
Complex polyketide metabolites, such as macrolides, polyenes, and polyethers, are an important source of novel therapeutics or… 
2006
2006
Dissection of the Late Steps in Aureothin Biosynthesis
Aureothin (1) is a rare nitrophenyl-substituted polyketide metabolite from Streptomyces thioluteus that has cytostatic properties… 
2005
2005
A short total synthesis of aureothin and N-acetylaureothamine.
The total synthesis of the nitrophenyl pyrones, (+/-)-aureothin and (+/-)-N-acetylaureothamine, starting from known 2-ethyl-6… 
2005
2005
Stereoselective syntheses of the bioactive polypropionates aureothin, N-acetylaureothamine, and aureonitrile.
[reaction: see text] Concise total syntheses of the bioactive polypropionates aureothin, N-acetylaureothamine, and aureonitrile… 
1955
1955
Mycolutein, a new antifungal antibiotic.
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