aspidospermidine
National Institutes of Health
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Aspidospermidine, vincadifformine, 1,2-dehydroaspidospermidine, goniomitine, and quebrachamine, five Aspidosperma alkaloids…
Pyrrole and pyrroldine heterocycles are ubiquitous structural features in natural products. Nature’s biosynthetic machinery often…
The total syntheses of a wide range of terrestrially derived alkaloids, especially ones isolated from members of the…
This thesis is concerned with the total synthesis of the two Aspidosperma alkaloid natural products, aspidospermidine and…
[reaction: see text] A formal synthesis of the Aspidosperma alkaloids aspidospermidine, aspidospermine, and quebrachamine is…
An iodoazide radical cascade cyclization strategy has been used as the key step in a formal synthesis of aspidospermidine…
(E)-5-(N-Benzylformimidoyl)-4-methylthiazole 3 was prepared in good yield from 5-formyl-4-methylthiazole and benzylamine…
A new method of synthesizing the alkaloid aspidospermidine (1), based on building ring E on the pyridocarbazole [ABCD] ring…
Two Bolivian Aspidosperma species were investigated. The seed and stem bark of Aspidosperma macrocarpon Mart. contain six known…
Transannular cydization of the iminium salt of dihydrocleavamine yields a compound with an As#do. sperma skeleton. X-ray analysis…