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artemisic acid

Known as: artemisinic acid 
National Institutes of Health

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Broader (1)

Artemisinins

Papers overview

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Highly Cited
2016
Highly Cited
2016
Rewriting yeast central carbon metabolism for industrial isoprenoid production
A bio-based economy has the potential to provide sustainable substitutes for petroleum-based products and new chemical building… 
Highly Cited
2013
Highly Cited
2013
High-level semi-synthetic production of the potent antimalarial artemisinin
In 2010 there were more than 200 million cases of malaria, and at least 655,000 deaths. The World Health Organization has… 
Highly Cited
2012
Highly Cited
2012
Production of amorphadiene in yeast, and its conversion to dihydroartemisinic acid, precursor to the antimalarial agent artemisinin
Malaria, caused by Plasmodium sp, results in almost one million deaths and over 200 million new infections annually. The World… 
Highly Cited
2012
Highly Cited
2012
Continuous-flow synthesis of the anti-malaria drug artemisinin.
Malaria remains a major global health problem, killing about one million people each year, with the protozoan parasite Plasmodium… 
Highly Cited
2012
Highly Cited
2012
The jasmonate-responsive AP2/ERF transcription factors AaERF1 and AaERF2 positively regulate artemisinin biosynthesis in Artemisia annua L.
Plants of Artemisia annua produce artemisinin, a sesquiterpene lactone widely used in malaria treatment. Amorpha-4,11-diene… 
Review
2010
Review
2010
The Biosynthesis of Artemisinin (Qinghaosu) and the Phytochemistry of Artemisia annua L. (Qinghao)
The Chinese medicinal plant Artemisia annua L. (Qinghao) is the only known source of the sesquiterpene artemisinin (Qinghaosu… 
Highly Cited
2010
Highly Cited
2010
Nicotiana benthamiana as a Production Platform for Artemisinin Precursors
Background Production of pharmaceuticals in plants provides an alternative for chemical synthesis, fermentation or natural… 
Highly Cited
2006
Highly Cited
2006
Production of the antimalarial drug precursor artemisinic acid in engineered yeast
Malaria is a global health problem that threatens 300–500 million people and kills more than one million people annually. Disease… 
Highly Cited
2000
Highly Cited
2000
Seasonal variation of artemisinin and its biosynthetic precursors in plants of Artemisia annua of different geographical origin: proof for the existence of chemotypes.
The time course of the levels of artemisinin, its biosynthetic precursors and the biosynthetically related sesquiterpenes was… 
Highly Cited
1999
Highly Cited
1999
Amorpha-4,11-diene synthase catalyses the first probable step in artemisinin biosynthesis.
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