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artemisic acid

Known as: artemisinic acid 
 
National Institutes of Health

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Related topics

1 relation

Broader (1)

Artemisinins

Papers overview

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Highly Cited
2016
Highly Cited
2016
Rewriting yeast central carbon metabolism for industrial isoprenoid production
A bio-based economy has the potential to provide sustainable substitutes for petroleum-based products and new chemical building… Expand
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2016
2016
A new synthetic biology approach allows transfer of an entire metabolic pathway from a medicinal plant to a biomass crop
Artemisinin-based therapies are the only effective treatment for malaria, the most devastating disease in human history. To meet… Expand
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Highly Cited
2013
Highly Cited
2013
High-level semi-synthetic production of the potent antimalarial artemisinin
In 2010 there were more than 200 million cases of malaria, and at least 655,000 deaths. The World Health Organization has… Expand
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Highly Cited
2012
Highly Cited
2012
Production of amorphadiene in yeast, and its conversion to dihydroartemisinic acid, precursor to the antimalarial agent artemisinin
Malaria, caused by Plasmodium sp, results in almost one million deaths and over 200 million new infections annually. The World… Expand
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Highly Cited
2012
Highly Cited
2012
The jasmonate-responsive AP2/ERF transcription factors AaERF1 and AaERF2 positively regulate artemisinin biosynthesis in Artemisia annua L.
Plants of Artemisia annua produce artemisinin, a sesquiterpene lactone widely used in malaria treatment. Amorpha-4,11-diene… Expand
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Highly Cited
2011
Highly Cited
2011
Generation of the potent anti-malarial drug artemisinin in tobacco
volume 29 number 12 DeCember 2011 nature biotechnology To the Editor: The emergence of multidrug-resistant strains of Plasmodium… Expand
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Highly Cited
2010
Highly Cited
2010
Nicotiana benthamiana as a Production Platform for Artemisinin Precursors
BACKGROUND Production of pharmaceuticals in plants provides an alternative for chemical synthesis, fermentation or natural… Expand
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Highly Cited
2009
Highly Cited
2009
Salicylic acid activates artemisinin biosynthesis in Artemisia annua L.
This paper provides evidence that salicylic acid (SA) can activate artemisinin biosynthesis in Artemisia annua L. Exogenous… Expand
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Highly Cited
2008
Highly Cited
2008
Induction of multiple pleiotropic drug resistance genes in yeast engineered to produce an increased level of anti-malarial drug precursor, artemisinic acid
BackgroundDue to the global occurrence of multi-drug-resistant malarial parasites (Plasmodium falciparum), the anti-malarial drug… Expand
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Highly Cited
2006
Highly Cited
2006
Production of the antimalarial drug precursor artemisinic acid in engineered yeast
Malaria is a global health problem that threatens 300–500 million people and kills more than one million people annually. Disease… Expand
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