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arctiin

Known as: 2(3H)-Furanone, 4-((3,4-dimethoxyphenyl)methyl)-3-((4-(beta-D-glucopyranosyloxy)-3-methoxyphenyl)methyl)dihydro-, (3R-trans)- (9CI), Arctigenin-4-glucoside 
A substance found in certain plants, including burdock. It has shown anticancer effects. Arctiin belongs to a group of substances called lignans.
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

FuransGlucosides

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Overview of the anti-inflammatory effects, pharmacokinetic properties and clinical efficacies of arctigenin and arctiin from Arctium lappa L
Arctigenin (AR) and its glycoside, arctiin, are two major active ingredients of Arctium lappa L (A lappa), a popular medicinal… 
Highly Cited
2015
Highly Cited
2015
Natural lignans from Arctium lappa as antiaging agents in Caenorhabditis elegans.
Highly Cited
2013
Highly Cited
2013
Arctigenin ameliorates inflammation in vitro and in vivo by inhibiting the PI3K/AKT pathway and polarizing M1 macrophages to M2-like macrophages.
Highly Cited
2010
Highly Cited
2010
Therapeutic effect of arctiin and arctigenin in immunocompetent and immunocompromised mice infected with influenza A virus.
Arctiin and its aglucone, arctigenin from the fruits of Arctium lappa L. showed potent in vitro antiviral activities against… 
Highly Cited
2010
Highly Cited
2010
Metabolic profile of the bioactive compounds of burdock (Arctium lappa) seeds, roots and leaves.
Highly Cited
2010
Highly Cited
2010
Anti-inflammatory function of arctiin by inhibiting COX-2 expression via NF-κB pathways
BackgroundArctiin, isolated from Forsythia suspensa has been reported to have anti-inflammatory, anti-oxidant, antibacterial, and… 
2010
2010
Lignans inhibit cell growth via regulation of Wnt/beta-catenin signaling.
Highly Cited
2005
Highly Cited
2005
Isolation, structure elucidation and bioactivity of schischkiniin, a unique indole alkaloid from the seeds of Centaurea schischkinii
Highly Cited
2003
Highly Cited
2003
Transformation of arctiin to estrogenic and antiestrogenic substances by human intestinal bacteria.
After anaerobic incubation of arctiin (1) from the seeds of Arctium lappa with a human fecal suspension, six metabolites were… 
Highly Cited
2000
Highly Cited
2000
Anti-tumor-promoting activity of lignans from the aerial part of Saussurea medusa.
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