Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

arctiin

Known as: 2(3H)-Furanone, 4-((3,4-dimethoxyphenyl)methyl)-3-((4-(beta-D-glucopyranosyloxy)-3-methoxyphenyl)methyl)dihydro-, (3R-trans)- (9CI), Arctigenin-4-glucoside 
A substance found in certain plants, including burdock. It has shown anticancer effects. Arctiin belongs to a group of substances called lignans.
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

FuransGlucosides

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Arctigenin but not arctiin acts as the major effective constituent of Arctium lappa L. fruit for attenuating colonic inflammatory response induced by dextran sulfate sodium in mice.
The crude powder of the fruit of Arctium lappa L. (ALF) has previously been reported to attenuate experimental colitis in mice… Expand
Is this relevant?
Highly Cited
2013
Highly Cited
2013
Arctigenin ameliorates inflammation in vitro and in vivo by inhibiting the PI3K/AKT pathway and polarizing M1 macrophages to M2-like macrophages.
Seeds of Arctium lappa, containing arctigenin and its glycoside arctiin as main constituents, have been used as a diuretic, anti… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2010
Highly Cited
2010
Therapeutic effect of arctiin and arctigenin in immunocompetent and immunocompromised mice infected with influenza A virus.
Arctiin and its aglucone, arctigenin from the fruits of Arctium lappa L. showed potent in vitro antiviral activities against… Expand
  • table 1
  • table 2
  • figure 2
  • table 3
  • figure 1
Is this relevant?
Highly Cited
2010
Highly Cited
2010
Anti-inflammatory function of arctiin by inhibiting COX-2 expression via NF-κB pathways
BackgroundArctiin, isolated from Forsythia suspensa has been reported to have anti-inflammatory, anti-oxidant, antibacterial, and… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2010
Highly Cited
2010
Metabolic profile of the bioactive compounds of burdock (Arctium lappa) seeds, roots and leaves.
In this work the bioactive metabolic profile, the antioxidant activity and total phenolic content of burdock (Arctium lappa… Expand
Is this relevant?
2010
2010
On-line coupling of counter-current chromatography and macroporous resin chromatography for continuous isolation of arctiin from the fruit of Arctium lappa L.
In this work, we have developed a novel hybrid two-dimensional counter-current chromatography and liquid chromatography (2D CCC x… Expand
Is this relevant?
2009
2009
Ameliorative effects of arctiin from Arctium lappa on experimental glomerulonephritis in rats.
Membranous glomerulonephritis (MGN) remains the most common cause of adult-onset nephrotic syndrome in the world and up to 40% of… Expand
Is this relevant?
2008
2008
Arctiin induces cell growth inhibition through the down-regulation of cyclin D1 expression.
Arctiin is a major lignan constituent of Arctium lappa and has anti-cancer properties in animal models. It was recently reported… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2003
Highly Cited
2003
Transformation of arctiin to estrogenic and antiestrogenic substances by human intestinal bacteria.
After anaerobic incubation of arctiin (1) from the seeds of Arctium lappa with a human fecal suspension, six metabolites were… Expand
  • table 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2000
Highly Cited
2000
Effects of arctiin on PhIP-induced mammary, colon and pancreatic carcinogenesis in female Sprague-Dawley rats and MeIQx-induced hepatocarcinogenesis in male F344 rats.
Chemopreventive effects of arctiin, a lignan isolated from Arctium lappa (burdock) seeds, on the initiation or post initiation… Expand
Is this relevant?
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License
ACCEPT & CONTINUE