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arctiin
Known as:
2(3H)-Furanone, 4-((3,4-dimethoxyphenyl)methyl)-3-((4-(beta-D-glucopyranosyloxy)-3-methoxyphenyl)methyl)dihydro-, (3R-trans)- (9CI)
, Arctigenin-4-glucoside
A substance found in certain plants, including burdock. It has shown anticancer effects. Arctiin belongs to a group of substances called lignans.
National Institutes of Health
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2 relations
Broader (2)
Furans
Glucosides
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Overview of the anti-inflammatory effects, pharmacokinetic properties and clinical efficacies of arctigenin and arctiin from Arctium lappa L
Qiong Gao
,
Mengbi Yang
,
Z. Zuo
Acta Pharmacologica Sinica
2018
Corpus ID: 13681058
Arctigenin (AR) and its glycoside, arctiin, are two major active ingredients of Arctium lappa L (A lappa), a popular medicinal…
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Highly Cited
2015
Highly Cited
2015
Natural lignans from Arctium lappa as antiaging agents in Caenorhabditis elegans.
Shan Su
,
M. Wink
Phytochemistry
2015
Corpus ID: 35703710
Highly Cited
2013
Highly Cited
2013
Arctigenin ameliorates inflammation in vitro and in vivo by inhibiting the PI3K/AKT pathway and polarizing M1 macrophages to M2-like macrophages.
S. Hyam
,
In-Ah Lee
,
+5 authors
Dong-Hyun Kim
European journal of pharmacology
2013
Corpus ID: 40846613
Highly Cited
2010
Highly Cited
2010
Therapeutic effect of arctiin and arctigenin in immunocompetent and immunocompromised mice infected with influenza A virus.
K. Hayashi
,
Kazuto Narutaki
,
Y. Nagaoka
,
Toshimitsu Hayashi
,
S. Uesato
Biological & pharmaceutical bulletin
2010
Corpus ID: 18225185
Arctiin and its aglucone, arctigenin from the fruits of Arctium lappa L. showed potent in vitro antiviral activities against…
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Highly Cited
2010
Highly Cited
2010
Metabolic profile of the bioactive compounds of burdock (Arctium lappa) seeds, roots and leaves.
R. Ferracane
,
G. Graziani
,
M. Gallo
,
V. Fogliano
,
A. Ritieni
Journal of pharmaceutical and biomedical analysis
2010
Corpus ID: 11740709
Highly Cited
2010
Highly Cited
2010
Anti-inflammatory function of arctiin by inhibiting COX-2 expression via NF-κB pathways
Sungwon Lee
,
Seulmee Shin
,
+8 authors
Kyungjae Kim
Journal of Inflammation
2010
Corpus ID: 2731782
BackgroundArctiin, isolated from Forsythia suspensa has been reported to have anti-inflammatory, anti-oxidant, antibacterial, and…
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2010
2010
Lignans inhibit cell growth via regulation of Wnt/beta-catenin signaling.
Ji-Hye Yoo
,
Hee-Ju Lee
,
+5 authors
C. Nho
Food and chemical toxicology : an international…
2010
Corpus ID: 24036644
Highly Cited
2005
Highly Cited
2005
Isolation, structure elucidation and bioactivity of schischkiniin, a unique indole alkaloid from the seeds of Centaurea schischkinii
M. Shoeb
,
S. Çelik
,
+5 authors
S. Sarker
2005
Corpus ID: 53631507
Highly Cited
2003
Highly Cited
2003
Transformation of arctiin to estrogenic and antiestrogenic substances by human intestinal bacteria.
Li-Hua Xie
,
E. Ahn
,
T. Akao
,
A. Abdel-Hafez
,
N. Nakamura
,
M. Hattori
Chemical & pharmaceutical bulletin
2003
Corpus ID: 16914598
After anaerobic incubation of arctiin (1) from the seeds of Arctium lappa with a human fecal suspension, six metabolites were…
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Highly Cited
2000
Highly Cited
2000
Anti-tumor-promoting activity of lignans from the aerial part of Saussurea medusa.
M. Takasaki
,
T. Konoshima
,
K. Komatsu
,
H. Tokuda
,
H. Nishino
Cancer letters
2000
Corpus ID: 46677341
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