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arctiin

Known as: 2(3H)-Furanone, 4-((3,4-dimethoxyphenyl)methyl)-3-((4-(beta-D-glucopyranosyloxy)-3-methoxyphenyl)methyl)dihydro-, (3R-trans)- (9CI), Arctigenin-4-glucoside 
A substance found in certain plants, including burdock. It has shown anticancer effects. Arctiin belongs to a group of substances called lignans.
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

FuransGlucosides

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Overview of the anti-inflammatory effects, pharmacokinetic properties and clinical efficacies of arctigenin and arctiin from Arctium lappa L
Arctigenin (AR) and its glycoside, arctiin, are two major active ingredients of Arctium lappa L (A lappa), a popular medicinal… Expand
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Review
2016
Review
2016
Evolving role of adiponectin in cancer-controversies and update
Adiponectin (APN), an adipokine produced by adipocytes, has been shown to have a critical role in the pathogenesis of obesity… Expand
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Highly Cited
2014
Highly Cited
2014
Arctigenin but not arctiin acts as the major effective constituent of Arctium lappa L. fruit for attenuating colonic inflammatory response induced by dextran sulfate sodium in mice.
The crude powder of the fruit of Arctium lappa L. (ALF) has previously been reported to attenuate experimental colitis in mice… Expand
Highly Cited
2013
Highly Cited
2013
Arctigenin ameliorates inflammation in vitro and in vivo by inhibiting the PI3K/AKT pathway and polarizing M1 macrophages to M2-like macrophages.
Seeds of Arctium lappa, containing arctigenin and its glycoside arctiin as main constituents, have been used as a diuretic, anti… Expand
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Highly Cited
2010
Highly Cited
2010
Therapeutic effect of arctiin and arctigenin in immunocompetent and immunocompromised mice infected with influenza A virus.
Arctiin and its aglucone, arctigenin from the fruits of Arctium lappa L. showed potent in vitro antiviral activities against… Expand
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Highly Cited
2010
Highly Cited
2010
Anti-inflammatory function of arctiin by inhibiting COX-2 expression via NF-κB pathways
BackgroundArctiin, isolated from Forsythia suspensa has been reported to have anti-inflammatory, anti-oxidant, antibacterial, and… Expand
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2009
2009
Ameliorative effects of arctiin from Arctium lappa on experimental glomerulonephritis in rats.
Membranous glomerulonephritis (MGN) remains the most common cause of adult-onset nephrotic syndrome in the world and up to 40% of… Expand
2008
2008
Natural Arctium lappa fruit extract improves the clinical signs of aging skin
Background  Subclinical, chronic tissue inflammation involving the generation of cytokines (e.g., interleukin‐6 and tumor… Expand
Highly Cited
2003
Highly Cited
2003
Transformation of arctiin to estrogenic and antiestrogenic substances by human intestinal bacteria.
After anaerobic incubation of arctiin (1) from the seeds of Arctium lappa with a human fecal suspension, six metabolites were… Expand
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Highly Cited
2000
Highly Cited
2000
Effects of arctiin on PhIP-induced mammary, colon and pancreatic carcinogenesis in female Sprague-Dawley rats and MeIQx-induced hepatocarcinogenesis in male F344 rats.
Chemopreventive effects of arctiin, a lignan isolated from Arctium lappa (burdock) seeds, on the initiation or post initiation… Expand
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