Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

aptiganel

Known as: Guanidine, N-(3-ethylphenyl)-N-methyl-N'-1-naphthalenyl 
 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2004
Review
2004
It has long been accepted that high concentrations of glutamate can destroy neurons, and this is the basis of the theory of… Expand
Is this relevant?
Review
2002
Review
2002
Glutamate N-methyl-D-aspartate (NMDA) receptor antagonists (competitive receptor antagonists, ion channel blockers, and glycine… Expand
  • figure 1
  • figure 2
Is this relevant?
2002
2002
SUMMARY During cerebral ischaemia, glutamate is released in supraphysiological amounts and is toxic to brain tissue. This… Expand
Is this relevant?
2001
2001
  • 2001
  • Corpus ID: 195161647
 
Is this relevant?
1998
1998
Recent studies have demonstrated a neuroprotective effect of the noncompetitive N-methyl-D-aspartate receptor antagonist… Expand
Is this relevant?
1998
1998
Recent studies revealed a neuroprotective effect of the non-competitive NMDA receptor antagonist Aptiganel HCL (Cerestat CNS 1102… Expand
Is this relevant?
1998
1998
BACKGROUND This study determined the induction profiles of immediate-early genes in the ovine brain after cardiopulmonary bypass… Expand
Is this relevant?
Review
1997
Review
1997
A wealth of experimental evidence demonstrates that cerebral ischemia cause excessive release of glutamate and that glutamate… Expand
  • table 1
  • table 3
  • table 4
Is this relevant?
1997
1997
The N-methyl-D-aspartate (NMDA) receptor is a ligand-gated ion channel which is widely distributed in the central nervous system… Expand
Is this relevant?